Dionisio Francisco, Baquero Fernando, Fuertes Marina
cE3c - Center for Ecology, Evolution and Environmental Change, CHANGE - Global Change and Sustainability Institute, & Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal; Departamento de Biologia Vegetal, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.
Departamento de Microbiología, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), and Centro de Investigación Médica en Red - Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Trends Microbiol. 2023 Jun;31(6):559-570. doi: 10.1016/j.tim.2022.12.010. Epub 2023 Jan 30.
Humans have inundated the environment worldwide with antimicrobials for about one century, giving selective advantage to antibiotic-resistant bacteria. Therefore, antibiotic resistance has become a public health problem responsible for increased mortality and extended hospital stays because the efficacy of antibiotics has diminished. Hospitals and other clinical settings have implemented stewardship measures to reduce antibiotic administration and prescription. However, these measures demand multifactorial approaches, including multidisciplinary teams in clinical settings and the education of professionals and patients. Recent studies indicate that individual factors, such as mother-infant attachment and parenting styles, play a critical role in antibiotic use. Also, macrocontextual factors, such as economic, social, or cultural backgrounds, may impact antibiotic use rates. Therefore, research aiming to ameliorate stewardship measures must include psychologically and sociologically based research.
大约一个世纪以来,人类在全球范围内大量使用抗菌药物,这使得对抗生素具有耐药性的细菌获得了选择性优势。因此,抗生素耐药性已成为一个公共卫生问题,导致死亡率上升和住院时间延长,因为抗生素的疗效已经下降。医院和其他临床机构已采取管理措施来减少抗生素的使用和处方。然而,这些措施需要多方面的方法,包括临床环境中的多学科团队以及对专业人员和患者的教育。最近的研究表明,个体因素,如母婴依恋和育儿方式,在抗生素使用中起着关键作用。此外,宏观背景因素,如经济、社会或文化背景,可能会影响抗生素的使用率。因此,旨在改善管理措施的研究必须包括基于心理学和社会学的研究。