Department of Surgery, University of Alberta, Edmonton, AB, Canada.
Centre for Advancement of Surgical Education and Simulation (CASES), Royal Alexandra Hospital, Edmonton, AB, Canada.
Surg Endosc. 2023 May;37(5):3893-3900. doi: 10.1007/s00464-023-09898-8. Epub 2023 Jan 31.
With expansion of bariatric surgery indications to include Asian patients with diabetes and body mass index (BMI) ≥ 27.5, or BMI ≥ 32.5, it is important to characterize Asian patient population undergoing bariatric surgery and assess their postoperative outcomes.
This retrospective study analyzed the 2015-2019 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) database. All patients undergoing Roux-en-Y gastric bypass (RYGB) and laparoscopic sleeve gastrectomy (LSG) who self-reported as Asian or White race were included. The primary outcomes were to characterize the Asian race population in North American and to identify if Asian race was associated with serious complications or mortality at 30 days.
Overall, 594,837 patients met inclusion, with 4229 self-reporting Asian racial status. Patients of Asian race were younger (41.8 vs 45.5 years, p < 0.001) and had a lower BMI (42.8 vs 44.7 kg/m p < 0.001) than White patients. They were also more likely to have insulin dependent diabetes (10.9% vs 8.2%, p < 0.001), have received prior cardiac surgery (10.0% vs 1.2% p < 0.001), and suffer from renal insufficiency (1.0% vs 0.5%, p < 0.001). There were no significant differences between rates of RYGB (28.3% vs 28.9%, p = 0.4) and mean operative duration (87.7 vs 87.5 min, p = 0.7). Additionally, there were no differences in 30 day outcomes including leak (0.5% vs 0.5%, p = 0.625), bleeding (1.2% vs 1.0%, p = 0.1), serious complications (3.4% vs 3.5%, p = 0.6), or mortality (0.1% vs 0.1%, p = 0.7) and after confounder control, Asian race was not independently associated with serious complications (OR 1.0, CI 0.9-1.2, p = 0.7), or mortality (OR 1.1, CI 0.3-3.3, p = 0.1).
Despite the increased metabolic burden of Asian patients, no differences in 30-day outcomes compared to White patients occurs. This data supports evidence suggesting these patients may safely undergo bariatric surgery independent of their increased metabolic burden.
随着减重手术适应证扩大到包括亚洲糖尿病患者和 BMI≥27.5 或 BMI≥32.5 的患者,描述接受减重手术的亚洲患者人群并评估其术后结局非常重要。
本回顾性研究分析了 2015 年至 2019 年代谢和减重手术认证和质量改进计划(MBSAQIP)数据库。纳入所有报告为亚洲或白种人种族并接受 Roux-en-Y 胃旁路术(RYGB)和腹腔镜袖状胃切除术(LSG)的患者。主要结局是描述北美亚洲人种的特征,并确定亚洲人种与 30 天内严重并发症或死亡率之间是否存在关联。
总体而言,594837 名患者符合纳入标准,其中 4229 名自我报告为亚洲人种。亚洲人种患者更年轻(41.8 岁 vs 45.5 岁,p<0.001),BMI 更低(42.8 千克/米 vs 44.7 千克/米,p<0.001)。他们也更有可能患有胰岛素依赖型糖尿病(10.9% vs 8.2%,p<0.001)、接受过心脏手术(10.0% vs 1.2%,p<0.001)和患有肾功能不全(1.0% vs 0.5%,p<0.001)。RYGB 率(28.3% vs 28.9%,p=0.4)和平均手术时间(87.7 分钟 vs 87.5 分钟,p=0.7)无显著差异。此外,30 天的结局包括漏诊(0.5% vs 0.5%,p=0.625)、出血(1.2% vs 1.0%,p=0.1)、严重并发症(3.4% vs 3.5%,p=0.6)或死亡率(0.1% vs 0.1%,p=0.7)无差异,经过混杂因素控制后,亚洲人种与严重并发症(OR 1.0,95%CI 0.9-1.2,p=0.7)或死亡率(OR 1.1,95%CI 0.3-3.3,p=0.1)无关。
尽管亚洲患者的代谢负担增加,但与白人患者相比,30 天结局无差异。这些数据支持了这样的证据,即这些患者可以安全地接受减重手术,而不会增加代谢负担。