Physiology Unit, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Ås, Norway.
Stress Environnementaux et BIOsurveillance des milieux aquatiques UMR-I 02 SEBIO, Université Le Havre Normandie, Le Havre, France.
Sci Data. 2023 Jan 31;10(1):62. doi: 10.1038/s41597-023-01967-w.
Directing both organismal homeostasis and physiological adaptation, the pituitary is a key endocrine gland in all vertebrates. One of its major tasks is to coordinate sexual maturation through the production and release of hormones stimulating gonad development. In order to study its developmental dynamics in the model fish medaka (Oryzias latipes), we sampled both the pituitary and the ovaries of 68 female fish. Of these, 55 spanned the entire course of sexual maturation from prepubertal juveniles to spawning adults. An additional 13 showed either considerably faster or slower growth and development than the majority of fish. We used histological examination of the ovaries to determine a histological maturation stage, and analyzed the pituitary glands using RNA-seq optimized for low input. Taken together, these data reveal the timing of hormone production priorities, and form a comprehensive resource for the study of their regulation.
作为所有脊椎动物的关键内分泌腺，垂体既调节着机体的内稳态，又调控着生理适应。其主要任务之一是通过产生和释放刺激性腺发育的激素来协调性成熟。为了研究其在模式鱼斑马鱼（Oryzias latipes）中的发育动态，我们对 68 条雌性斑马鱼的垂体和卵巢进行了采样。其中，55 条鱼涵盖了从青春期前的幼鱼到产卵成年鱼的整个性成熟过程。另外 13 条鱼的生长和发育速度明显快于或慢于大多数鱼。我们使用卵巢的组织学检查来确定组织学成熟阶段，并使用针对低输入优化的 RNA-seq 分析垂体。这些数据共同揭示了激素产生优先级的时间，并为研究其调控提供了全面的资源。
