Université de Franche-Comté, Laboratoire de Recherches Intégratives en Neurosciences et Psychologie Cognitive & MSHE Ledoux, CNRS, Besançon F-25000, France.
Laboratoire d'Etude des Mécanismes Cognitifs (EA 3082), Université Lyon 2, Bron, France.
Cereb Cortex. 2023 May 24;33(11):6526-6542. doi: 10.1093/cercor/bhac522.
Our ability to understand how to interact with familiar objects is supported by conceptual tool knowledge. Conceptual tool knowledge includes action tool and semantic tool knowledge which are supported by the ventro-dorsal and the ventral pathways, respectively. This apparent functional segregation has been recently called into question. In a block-design fMRI study, 35 participants were asked to complete manipulation, function, and association judgment tasks about pairs of familiar objects. Our results showed that lateral occipitotemporal cortex in the ventral pathway was more sensitive to manipulation and function judgment tasks compared with association judgment tasks. Functional connectivity analyses revealed distinct coupling patterns between inferior parietal lobule, lateral occipitotemporal cortex, and fusiform gyrus. Taken together, these data indicate that action tool and semantic tool knowledge are both supported by ventral and ventro-dorsal pathways. Moreover, the explicit retrieval of these representations is supported by the functional coupling of common and distinct brain regions of the posterior tool processing network varying according to the kind of relations to be retrieved.
我们理解如何与熟悉的物体互动的能力是由概念工具知识支持的。概念工具知识包括动作工具和语义工具知识，它们分别由腹侧和背侧通路支持。这种明显的功能分离最近受到了质疑。在一项基于块设计的 fMRI 研究中，35 名参与者被要求完成关于一对熟悉物体的操作、功能和联想判断任务。我们的结果表明，与联想判断任务相比，腹侧通路中的外侧枕颞叶皮层对操作和功能判断任务更敏感。功能连接分析揭示了下顶叶、外侧枕颞叶皮层和梭状回之间的不同耦合模式。总之，这些数据表明，动作工具和语义工具知识都由腹侧和背侧通路支持。此外，这些表示的显式检索是由后部工具处理网络中常见和不同脑区的功能耦合支持的，其根据要检索的关系的种类而变化。
