Razdan Ankur, Schropp Lars, Vaeth Michael, Kirkevang Lise-Lotte
Section for Oral Radiology and Endodontics, Department of Dentistry and Oral Health, Aarhus University, Aarhus, Denmark.
Department of Public Health, Aarhus University, Aarhus, Denmark.
Int Endod J. 2023 May;56(5):558-572. doi: 10.1111/iej.13901. Epub 2023 Mar 6.
The aim of the study was to compare the frequency of root filled teeth and quality of root fillings (RFs) in two parallel, Danish cohorts each examined over 10 years and to evaluate factors associated with apical periodontitis (AP) and extraction of root filled teeth.
Two randomly selected cohorts (C1, C2) from Aarhus (age: 20-64 years) were followed for approximately 10 years, with full-mouth radiographic surveys performed at 5-year intervals (C1: 1997-2003-2008; C2: 2009-2014-2019). Frequency of root filled teeth, quality of RFs and coronal restorations, periapical status and tooth extraction were registered. Logistic regression analyses compared C1 with C2 for baseline and follow-up periods and assessed variables associated with AP (PAI-based) and extraction of root filled teeth.
C1 included 330 and C2, 170 individuals, mean age 42.9 and 47.3 years, respectively, who attended all three radiographic examinations. The relative frequency of root filled teeth was lower in C2 than C1 at baseline (C1: 4.7%, C2: 3.6%; p < .001) and after 10 years (C1: 5.7%, C2: 4.2%; p < .001). The relative frequency of new RFs was lower in C2 than in C1 (p = .02). C2 had fewer short/long RFs at baseline than C1; quality of new RFs or coronal restorations was similar in C1 and C2. The risk of tooth extraction (p = .93) and risk of AP (p = .37) at 10-year follow-up was similar between the two cohorts. For both C1 and C2, root filled teeth with AP at baseline had increased risk of having AP (p < .001) or having been extracted (p < .001) at follow-up. Risk of extraction was higher for root filled premolars (p = .01) and molars (p = .01) than anteriors. Risk of AP at follow-up was higher for root filled molars (p < .001). Furthermore, inadequate quality of RFs (p = .02) and coronal restorations (p = .04) increased the risk of AP at follow-up in C1 and C2.
The frequency of root filled teeth and new RFs decreased and little to no change in new RFs' quality, AP, or tooth extraction was seen over time (1997-2019). Root filled molars and teeth with AP at baseline had increased risk of AP and extraction.
本研究旨在比较两个平行的丹麦队列中根管充填牙的频率和根管充填质量（RFs），这两个队列均经过了10年的检查，并评估与根尖周炎（AP）和根管充填牙拔除相关的因素。
从奥胡斯随机选取两个队列（C1、C2）（年龄：20 - 64岁），随访约10年，每隔5年进行一次全口影像学检查（C1：1997 - 2003 - 2008；C2：2009 - 2014 - 2019）。记录根管充填牙的频率、RFs和冠部修复体的质量、根尖周状况及牙齿拔除情况。逻辑回归分析比较了C1和C2在基线期和随访期的情况，并评估与AP（基于PAI）和根管充填牙拔除相关的变量。
C1有330人，C2有170人，平均年龄分别为42.9岁和47.3岁，所有受试者均参加了三次影像学检查。基线时C2中根管充填牙的相对频率低于C1（C1：4.7%，C2：3.6%；p <.001），10年后同样如此（C1：5.7%，C2：4.2%；p <.001）。C2中新RFs的相对频率低于C1（p = 0.02）。基线时C2的短/长RFs比C1少；C1和C2中新RFs或冠部修复体的质量相似。两个队列在10年随访时牙齿拔除风险（p = 0.93）和AP风险（p = 0.37）相似。对于C1和C2，基线时患有AP的根管充填牙在随访时发生AP（p <.001）或被拔除（p <.001）的风险增加。根管充填的前磨牙（p = 0.01）和磨牙（p = 0.01）的拔除风险高于前牙。随访时根管充填磨牙的AP风险更高（p <.001）。此外，RFs（p = 0.02）和冠部修复体质量不足（p = 0.04）会增加C1和C2随访时AP的风险。
随着时间推移（1997 - 2019年），根管充填牙和新RFs的频率下降，新RFs质量、AP或牙齿拔除几乎没有变化。基线时根管充填的磨牙和患有AP的牙齿发生AP和被拔除的风险增加。
