Optogenetics & Synthetic Biology Interdisciplinary Research Center, State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, 130# Meilong Road, Shanghai 200237, China.
School of Mechanics, East China University of Science and Technology, 130# Meilong Road, Shanghai, 200237, China.
Chem Commun (Camb). 2023 Feb 14;59(14):1963-1966. doi: 10.1039/d2cc05677a.
A facile hydrogel fabrication strategy based on a simultaneous dual-photo-coupling reaction (, photoinduced -nitrosylation and Schiff base reaction) was reported. This strategy allowed a strengthened three-arm crosslinking network to form in one step and the hydrogels obtained displayed rapid gelation, excellent mechanical strength and biocompatibility for cell encapsulated-3D printing in real time. Our hydrogel fabrication strategy will likely foster advances in biomaterials and the extreme speed and reinforced mechanical strength should significantly benefit 3D printing and related applications.
本文报道了一种基于同步双重光偶联反应（光诱导亚硝化和席夫碱反应）的简便水凝胶制备策略。该策略允许在一步中形成强化的三臂交联网络，所得水凝胶表现出快速凝胶化、优异的机械强度和生物相容性，可用于实时细胞包封的 3D 打印。我们的水凝胶制备策略有望推动生物材料的发展，并且极快的速度和增强的机械强度将显著有益于 3D 打印及相关应用。
