School of Pharmaceutical Science, University of South China, Hengyang 421001, Hunan, PR China.
School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, Hunan, PR China.
Anal Methods. 2023 Feb 16;15(7):944-950. doi: 10.1039/d2ay01793h.
Camphor leaves were used as the precursor for the hydrothermal synthesis of carbon quantum dots. The preparation method is simple and rapid, and the raw material is environmentally friendly and easy to obtain. Without additional modification, the carbon quantum dots were used as fluorescent probes for the sensitive and selective detection of Fe and isoniazid at different excitation wavelengths. For Fe, at the excitation wavelength of 320 nm, the ratio of fluorescence intensity of CQD solution after adding Fe to CQD solution without Fe addition, /, and Fe concentration showed a good linear relationship in the range of 2.72 × 10 to 1.00 × 10 mol L ( = 0.9912), and the limit of detection was 8.16 μmol L. For isoniazid, at the excitation wavelength of 270 nm, the ratio of fluorescence intensity of CQDs solution with isoniazid to CQDs solution without isoniazid, /, and isoniazid concentration showed good linear relationships in the range of 3.81 × 10 to 1.00 × 10 mol L ( = 0.9941) and 1.00 × 10 to 2.10 × 10 mol L ( = 0.9910) respectively, and the limit of detection was 1.14 μmol L. A fluorescence method for the determination of Fe and isoniazid content was proposed. The method has been used to detect iron in iron supplement tablets and isoniazid in isoniazid tablets with satisfactory results.
樟树叶被用作水热合成碳量子点的前体。该制备方法简单快速，原料环保易得。未经额外修饰，碳量子点即可用作荧光探针，用于在不同激发波长下对 Fe 和异烟肼进行灵敏和选择性检测。对于 Fe，在 320nm 的激发波长下，加入 Fe 后 CQD 溶液的荧光强度与未加入 Fe 的 CQD 溶液的荧光强度之比，/，与 Fe 浓度在 2.72×10 到 1.00×10 mol L 范围内呈现良好的线性关系（=0.9912），检出限为 8.16μmol L。对于异烟肼，在 270nm 的激发波长下，加入异烟肼后 CQDs 溶液的荧光强度与未加入异烟肼的 CQDs 溶液的荧光强度之比，/，与异烟肼浓度在 3.81×10 到 1.00×10 mol L 范围内呈现良好的线性关系（=0.9941）和 1.00×10 到 2.10×10 mol L 范围内呈现良好的线性关系（=0.9910），检出限为 1.14μmol L。提出了一种用于测定 Fe 和异烟肼含量的荧光法。该方法已用于铁补充片剂中铁和异烟肼片剂中异烟肼的测定，结果令人满意。
