• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

髋关节离断或半骨盆切除术患者的死亡率和生活质量的回顾性分析:15 例报告。

Retrospective analysis of mortality and quality of life after hip disarticulation or hemipelvectomy: a report on 15 patients.

机构信息

Department of Trauma Surgery, University Hospital Regensburg, Franz-Josef-Strauss-Allee 11, 93053, Regensburg, Germany.

出版信息

Arch Orthop Trauma Surg. 2023 Aug;143(8):4943-4949. doi: 10.1007/s00402-023-04783-4. Epub 2023 Feb 1.

DOI:10.1007/s00402-023-04783-4
PMID:36723759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10374469/
Abstract

BACKGROUND

Hip disarticulation and hemipelvectomy are defined as major ablative amputations of the lower limb. Due to the small number of patients, little is known about the outcome and follow-up.

AIMS

We aimed to assess (1) reasons for performed major ablative surgeries such as hip disarticulation and hemipelvectomy in a German center for trauma and orthopedic surgery. (2) In addition, mortality and quality of life after hip disarticulation and hemipelvectomy as well as (3) patient and treatment characteristics should be investigated.

METHODS

During a period of twelve years, 15 patients underwent hip disarticulation or hemipelvectomy. Mortality, EQ-5D-3L quality of life by EQ-5D-3L and time-trade-off (TTO), VAS, cause of disarticulation, length of hospital stays, revisions, comorbidities, Charlson comorbidity index (CCI), and ASA score were evaluated retrospective for all patients.

RESULTS

The overall mortality rates were 26.7% at 30 days, 60.0% after one year and 66.7% after three years. The five surviving patients reported about moderate problems in the EQ-5D-3L. The average VAS score reached 45 (range 15-65). The mean TTO was 9.8 (range 6-12). Indications for amputation were infection (n = 7), tumor (n = 6), trauma (n = 1) and ischemia (n = 1).

CONCLUSION

Hip disarticulation and hemipelvectomy are followed by a high postoperative mortality. Quality of life of the affected patients is impaired in long-term follow-up. Especially amputations performed due to infections show high mortality within one month after surgery despite average young age and low CCI. Surgeons should be aware of this devastating outcome and extraordinary vigilant for these vulnerable patient cohorts.

摘要

背景

髋关节离断术和半骨盆切除术被定义为下肢的主要破坏性截肢。由于患者数量较少,对于这些手术的结果和随访知之甚少。

目的

我们旨在评估(1)在德国创伤和矫形外科中心进行主要破坏性手术(如髋关节离断术和半骨盆切除术)的原因。(2)此外,还评估了髋关节离断术和半骨盆切除术的死亡率和生活质量,以及(3)患者和治疗特征。

方法

在 12 年期间,有 15 名患者接受了髋关节离断术或半骨盆切除术。对所有患者进行了回顾性评估,包括死亡率、EQ-5D-3L 生活质量(EQ-5D-3L 和时间权衡法[TTO])、VAS 评分、离断原因、住院时间、翻修、合并症、Charlson 合并症指数(CCI)和美国麻醉师协会(ASA)评分。

结果

术后 30 天、1 年和 3 年的总死亡率分别为 26.7%、60.0%和 66.7%。5 名存活患者报告在 EQ-5D-3L 中有中度问题。平均 VAS 评分为 45(范围 15-65)。平均 TTO 为 9.8(范围 6-12)。截肢的指征包括感染(n=7)、肿瘤(n=6)、创伤(n=1)和缺血(n=1)。

结论

髋关节离断术和半骨盆切除术的术后死亡率较高。受影响患者的生活质量在长期随访中受损。特别是由于感染而进行的截肢,尽管平均年龄较小且 CCI 较低,但在手术后一个月内死亡率很高。外科医生应该意识到这种毁灭性的结果,并对这些脆弱的患者群体保持高度警惕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/0ff7ce86aca7/402_2023_4783_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/22e230f49726/402_2023_4783_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/822a625bca2b/402_2023_4783_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/d6c13570f24a/402_2023_4783_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/148f432a81b7/402_2023_4783_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/7eb675fadd6c/402_2023_4783_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/0ff7ce86aca7/402_2023_4783_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/22e230f49726/402_2023_4783_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/822a625bca2b/402_2023_4783_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/d6c13570f24a/402_2023_4783_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/148f432a81b7/402_2023_4783_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/7eb675fadd6c/402_2023_4783_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48e4/10374469/0ff7ce86aca7/402_2023_4783_Fig6_HTML.jpg

相似文献

1
Retrospective analysis of mortality and quality of life after hip disarticulation or hemipelvectomy: a report on 15 patients.髋关节离断或半骨盆切除术患者的死亡率和生活质量的回顾性分析:15 例报告。
Arch Orthop Trauma Surg. 2023 Aug;143(8):4943-4949. doi: 10.1007/s00402-023-04783-4. Epub 2023 Feb 1.
2
Healthcare Utilization Following Hemipelvectomy or Hip Disarticulation in the Military Health System.军队卫生系统行半骨盆切除术或髋关节离断术后的医疗保健利用情况。
Mil Med. 2024 Jan 23;189(1-2):e235-e241. doi: 10.1093/milmed/usad295.
3
Factors affecting successful prosthetic use after hemipelvectomy and hip disarticulation amputations: Five-year experience from a tertiary prosthetic rehabilitation center.影响半骨盆切除和髋关节离断截肢术后假肢成功使用的因素:来自三级假肢康复中心的五年经验
Prosthet Orthot Int. 2024 Jan 1;48(1):20-24. doi: 10.1097/PXR.0000000000000226. Epub 2023 Mar 14.
4
Free fillet lower leg flap for coverage after hemipelvectomy or hip disarticulation.游离股前外侧皮瓣修复半骨盆切除或髋关节离断术后小腿创面。
Orthop Traumatol Surg Res. 2019 Feb;105(1):47-54. doi: 10.1016/j.otsr.2018.10.018. Epub 2018 Dec 27.
5
Proximal major limb amputations--a retrospective analysis of 45 oncological cases.近端大肢体截肢术——45例肿瘤病例的回顾性分析
World J Surg Oncol. 2009 Feb 9;7:15. doi: 10.1186/1477-7819-7-15.
6
Prosthetic Rehabilitation After Hip Disarticulation or Hemipelvectomy.髋关节离断术或半骨盆切除术后的假肢康复
Am J Phys Med Rehabil. 2015 Dec;94(12):1035-40. doi: 10.1097/PHM.0000000000000292.
7
Functional outcome of hip disarticulation and hemipelvectomy: a cross-sectional national descriptive study in the Netherlands.髋关节离断术和半骨盆切除术的功能结局:荷兰的一项全国性横断面描述性研究。
Clin Rehabil. 2008 Dec;22(12):1127-33. doi: 10.1177/0269215508095088.
8
Targeted muscle reinnervation following external hemipelvectomy or hip disarticulation: An anatomic description of technique and clinical case correlates.异体半骨盆切除术或髋关节离断术后的靶向肌肉神经再支配:技术解剖描述及临床病例相关性
J Surg Oncol. 2020 Dec;122(8):1693-1710. doi: 10.1002/jso.26189. Epub 2020 Sep 3.
9
Hip disarticulation - case series analysis and literature review.髋关节离断术——病例系列分析与文献综述
Rev Bras Ortop. 2017 Mar 3;52(2):154-158. doi: 10.1016/j.rboe.2016.09.008. eCollection 2017 Mar-Apr.
10
Major ablative procedures in orthopaedic surgery.骨科手术中的主要切除手术。
Bull Hosp Jt Dis. 1996;55(1):46-52.

引用本文的文献

1
Survival and risk factor analysis in patients with septic arthritis: a retrospective study of 192 cases.化脓性关节炎患者的生存及危险因素分析:一项192例病例的回顾性研究
BMC Infect Dis. 2025 Mar 18;25(1):374. doi: 10.1186/s12879-024-10316-0.
2
Dabigatran-induced Enterococcus Necrotizing Fasciitis in Medically Unfit Patient with Successful Conservative Treatment Outcome: A Case Report.达比加群酯致身体状况不佳患者发生肠球菌坏死性筋膜炎,保守治疗成功:一例报告
Malays Orthop J. 2024 Nov;18(3):80-83. doi: 10.5704/MOJ.2411.012.
3
Intramedullary Total Femur via a Direct Anterior Approach for Complex Revision Total Hip and Knee Arthroplasty.

本文引用的文献

1
External and internal hemipelvectomy: A retrospective analysis of 68 cases.内外侧半骨盆切除术:68例回顾性分析
Jt Dis Relat Surg. 2022;33(1):132-141. doi: 10.52312/jdrs.2022.560. Epub 2022 Mar 28.
2
Lower Limb Amputation Rates in Germany.德国下肢截肢率。
Medicina (Kaunas). 2022 Jan 10;58(1):101. doi: 10.3390/medicina58010101.
3
Emergency hip disarticulations for severe necrotising fasciitis of the lower limb: a series of rare cases from a rural district general hospital.下肢严重坏死性筋膜炎的急诊髋关节离断术:来自一家农村地区综合医院的一系列罕见病例
经直接前路行股骨髓内固定用于复杂翻修全髋关节和全膝关节置换术
Arthroplast Today. 2024 Aug 2;28:101474. doi: 10.1016/j.artd.2024.101474. eCollection 2024 Aug.
4
Midterm survival and risk factor analysis in patients with pyogenic vertebral osteomyelitis: a retrospective study of 155 cases.化脓性脊椎骨髓炎患者的中期生存及危险因素分析:一项155例病例的回顾性研究
Front Surg. 2024 May 21;11:1357318. doi: 10.3389/fsurg.2024.1357318. eCollection 2024.
Ann R Coll Surg Engl. 2021 Jul;103(7):e223-e226. doi: 10.1308/rcsann.2021.0079.
4
Hip Disarticulation : Retrospective Review of a Single Surgeon's Outcomes Over 15 Years.
Am Surg. 2021 Nov;87(11):1829-1830. doi: 10.1177/0003134820923341. Epub 2020 Jun 29.
5
Surgical and oncological outcomes after hindquarter amputation for pelvic sarcoma.骨盆肉瘤后后肢截肢的手术和肿瘤学结果。
Bone Joint J. 2020 Jun;102-B(6):788-794. doi: 10.1302/0301-620X.102B6.BJJ-2019-1317.R1.
6
Hip disarticulation - case series analysis and literature review.髋关节离断术——病例系列分析与文献综述
Rev Bras Ortop. 2017 Mar 3;52(2):154-158. doi: 10.1016/j.rboe.2016.09.008. eCollection 2017 Mar-Apr.
7
Survival rate and perioperative data of patients who have undergone hemipelvectomy: a retrospective case series.接受半骨盆切除术患者的生存率及围手术期数据:一项回顾性病例系列研究。
World J Surg Oncol. 2016 Oct 7;14(1):255. doi: 10.1186/s12957-016-1001-7.
8
Quality of life in war-related hip disarticulation in Iran.伊朗与战争相关的髋关节离断患者的生活质量
Acta Orthop Traumatol Turc. 2014;48(5):527-32. doi: 10.3944/AOTT.2014.13.0036.
9
Hip disarticulation for severe lower extremity infections.髋关节离断术用于治疗严重的下肢感染。
Clin Orthop Relat Res. 2009 Jul;467(7):1721-6. doi: 10.1007/s11999-009-0769-y. Epub 2009 Mar 10.
10
Functional outcome of hip disarticulation and hemipelvectomy: a cross-sectional national descriptive study in the Netherlands.髋关节离断术和半骨盆切除术的功能结局:荷兰的一项全国性横断面描述性研究。
Clin Rehabil. 2008 Dec;22(12):1127-33. doi: 10.1177/0269215508095088.