Gong Weidong, Qiu Shuang, Zheng Shiyu, Liu Wei, Zhang Chunyin
From the Department of Nuclear Medicine, The No. 2 People's Hospital of Yibin, Yibin.
Clin Nucl Med. 2023 Mar 1;48(3):273-275. doi: 10.1097/RLU.0000000000004479. Epub 2022 Dec 24.
Intracranial syphilitic gumma is a rare neurological disease. We present 68Ga-DOTA-FAPI-04 and 18F-FDG PET/CT findings of intracranial syphilitic gumma in a 46-year-old man with HIV. In this case, 68Ga-DOTA-FAPI-04 PET/CT outperforms 18F-FDG in helping to visualizing syphilitic gumma. Syphilitic gumma can also cause increase FAPI activity. Our findings suggest the potential value of 68Ga-DOTA-FAPI-04 in the diagnosis of syphilis.
颅内梅毒瘤是一种罕见的神经系统疾病。我们展示了一名46岁艾滋病男性患者颅内梅毒瘤的68Ga-DOTA-FAPI-04和18F-FDG PET/CT检查结果。在该病例中,68Ga-DOTA-FAPI-04 PET/CT在帮助显示梅毒瘤方面优于18F-FDG。梅毒瘤也可导致FAPI活性增加。我们的研究结果提示68Ga-DOTA-FAPI-04在梅毒诊断中的潜在价值。