El Haj Mohamad, Moustafa Ahmed A
Laboratoire de Psychologie des Pays de la Loire (LPPL - EA 4638), Nantes Université, Univ Angers Nantes, France.
Unité de Gériatrie, Centre Hospitalier de Tourcoing, Tourcoing, France.
Cogn Neuropsychiatry. 2023 Mar;28(2):116-129. doi: 10.1080/13546805.2023.2173059. Epub 2023 Feb 1.
Little research has investigated decision making in patients with Korsakoff syndrome (KS). Specifically, to our knowledge, there is a lack of research investigating whether patients with KS may tend to prefer immediate over future rewards (i.e., temporal discounting). Further, we investigated the relationship between temporal discounting and inhibition.
We, for the first time, invited patients with KS and control participants to perform a temporal discounting task, in which they answered questions probing preferences between an immediate, but smaller amount of money, and a delayed, but larger amount of money (e.g., "would you prefer 10 dollars today or 50 dollars after one month?"). Furthermore, inhibition was measured using the Stroop Colour Word Test.
Analysis demonstrated higher temporal discounting in patients with KS than in control participants. Temporal discounting in both populations was significantly correlated with inhibition.
Patients with KS may have difficulties to suppress the temptation of smaller, but immediate, rewards.
针对柯萨科夫综合征（KS）患者决策的研究较少。具体而言，据我们所知，缺乏关于KS患者是否倾向于偏好即时奖励而非未来奖励（即时间折扣）的研究。此外，我们研究了时间折扣与抑制之间的关系。
我们首次邀请KS患者和对照参与者执行一项时间折扣任务，在该任务中，他们回答有关在即时但金额较小的金钱与延迟但金额较大的金钱之间进行偏好选择的问题（例如，“你更喜欢今天得到10美元还是一个月后得到50美元？”）。此外，使用斯特鲁普颜色词测试来测量抑制能力。
分析表明，KS患者的时间折扣高于对照参与者。两组人群的时间折扣均与抑制能力显著相关。
KS患者可能难以抑制较小但即时奖励的诱惑。
