Bauerle Luke, Palmer Charles, Salazar Claudia A, Larrew Thomas, Kerns Suzanne E, Short E Baron, George Mark S, Rowland Nathan C
1College of Medicine, Medical University of South Carolina.
2Department of Psychiatry & Behavioral Sciences, Medical University of South Carolina.
Neurosurg Focus. 2023 Feb;54(2):E8. doi: 10.3171/2022.11.FOCUS22622.
Surgical techniques targeting behavioral disorders date back thousands of years. In this review, the authors discuss the history of neurosurgery for psychiatric disorders, starting with trephination in the Stone Age, progressing through the fraught practice of prefrontal lobotomy, and ending with modern neurosurgical techniques for treating psychiatric conditions, including ablative procedures, conventional deep brain stimulation, and closed-loop neurostimulation. Despite a tumultuous past, psychiatric neurosurgery is on the cusp of becoming a transformative therapy for patients with psychiatric dysfunction, with an ever-increasing evidence base suggesting reproducible and ethical therapeutic benefit.
针对行为障碍的外科技术可追溯到数千年前。在这篇综述中，作者们讨论了精神疾病神经外科手术的历史，从石器时代的环锯术开始，历经充满争议的前额叶白质切除术，到现代治疗精神疾病的神经外科技术，包括切除手术、传统深部脑刺激术和闭环神经刺激术。尽管过去历经波折，但精神疾病神经外科手术正处于成为治疗精神功能障碍患者变革性疗法的边缘，越来越多的证据表明其具有可重复且符合伦理的治疗益处。
