University of California, San Diego, United States of America.
Auburn University, Auburn, AL, United States of America.
J Affect Disord. 2023 Apr 1;326:155-162. doi: 10.1016/j.jad.2023.01.089. Epub 2023 Jan 30.
We examined the factor structure of Acute Suicidal Affective Disturbance (ASAD) in individuals with eating disorders. ASAD is a proposed diagnosis with four symptoms: rapidly increasing suicidal intent, social or self-alienation, hopelessness regarding the previous symptoms, and overarousal.
Patients with eating disorders (N = 378) completed self-report symptom questionnaires at admission to a partial hospitalization program for eating disorders. Using proxy measures, we conducted a confirmatory factor analysis (CFA) of the one-factor model of ASAD.
Initial model fit was poor. We iteratively revised the model to include theoretically-justified correlated residuals (i.e., those between items intended to measure the same ASAD symptom). After these modifications, model fit remained mediocre. We next conducted a multiple-group CFA to compare ASAD between individuals with the restricting subtype of anorexia nervosa (the "ANR" model, n = 145) and individuals with binge/purge disorders (i.e., bulimia nervosa and the binge-purge subtype of anorexia nervosa; the "BP" model, n = 234). The final model had mediocre fit with partial invariance between subgroups; the ASAD factor mean was higher in the BP model. We additionally tested a bifactor model, with similar findings.
Our use of proxy measures of ASAD items may have resulted in imprecise measurement of ASAD symptoms, pointing to the importance of future research using validated measures of ASAD.
We found moderate support for ASAD in an eating disorder sample, with invariance between eating disorder phenotypes. Our findings suggest that the ASAD diagnosis may not fully generalize to eating disorder samples.
我们研究了进食障碍患者中急性自杀情感障碍(ASAD)的因素结构。ASAD 是一种拟议的诊断,有四个症状:自杀意图迅速增加、社交或自我疏远、对以前症状感到绝望、过度兴奋。
患有进食障碍的患者(N=378)在参加进食障碍部分住院计划时完成了自我报告症状问卷。我们使用代理测量,对 ASAD 的单因素模型进行了验证性因素分析(CFA)。
初始模型拟合度较差。我们迭代地修改模型,包括理论上合理的相关残差(即那些用于测量相同 ASAD 症状的项目之间的残差)。在这些修改之后,模型拟合度仍然一般。我们接下来进行了一个多组 CFA,以比较限制型神经性厌食症(“ANR”模型,n=145)和暴食/清除障碍(即神经性贪食症和神经性贪食症的暴食/清除亚型;“BP”模型,n=234)个体之间的 ASAD。最终模型的拟合度中等,亚组之间存在部分不变性;BP 模型的 ASAD 因子均值较高。我们还测试了一个双因素模型,也有类似的发现。
我们使用 ASAD 项目的代理测量可能导致 ASAD 症状的测量不准确,这表明未来使用 ASAD 的验证性测量进行研究的重要性。
我们在进食障碍样本中发现了对 ASAD 的适度支持,进食障碍表型之间存在不变性。我们的发现表明,ASAD 诊断可能不完全适用于进食障碍样本。