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硬皮病的消化系统症状(作者译)

[Digestive symptoms of scleroderma (author's transl)].

作者信息

Puissant A, Roujeau J, Modigliani R, Katz M, Kuffer R, Blanchet-Bardon C

出版信息

Ann Dermatol Venereol. 1978 Aug-Sep;105(8-9):725-20.

PMID:367249
Abstract

The authors successively study the oral, peri-oral, esophageal, intestinal and anal manifestations of systemic scleroderma. They point out that dental, salivary, and esophageal involvement is of great interest for diagnosis and prognosis. They particularly describe the malabsorption syndrome including anatomical and ultrastructural lesions of the smooth muscle fibers. They present an original study of arrector pili in clinically and histologically non-involved skin of patients undergoing scleroderma. Finally they state that any suspected or diagnosed scleroderma needs a digestive check-up as follows: radiologic examination of the teeth, biopsy of the minor salivary glands of the lower lip, radiologic study of esophageal motility and radioactive C 14 glycocholate test.

摘要

作者先后研究了系统性硬皮病的口腔、口周、食管、肠道及肛门表现。他们指出,牙齿、唾液腺及食管受累情况对诊断和预后具有重要意义。他们特别描述了吸收不良综合征,包括平滑肌纤维的解剖学和超微结构病变。他们对硬皮病患者临床上和组织学上未受累皮肤的立毛肌进行了一项原创性研究。最后他们指出,任何疑似或确诊的硬皮病患者都需要进行如下消化系统检查:牙齿的放射学检查、下唇小唾液腺活检、食管动力的放射学研究以及放射性C 14甘氨胆酸盐试验。

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