Audebert M, Le Parco J C, Gendre J P, Le Quintrec Y
Nouv Presse Med. 1979 May 19;8(22):1839-41.
In CRST syndrome, latent oesophageal involvement is common but not usually associated with any clinical manifestations. Involvement of the small intestine is rare. In three patients there occurred severe complications related to digestive involvement in the condition. In one case, involvement of the small intestine was associated with functional obstruction. In the other two patients, oesophageal involvement progressed to very tight stenosis of the lower end of the eosophagus. The generally accepted bening nature of this form of scleroderma must therefore be questioned.
在CRST综合征中,食管潜在受累很常见,但通常无任何临床表现。小肠受累罕见。有3例患者出现了与该病消化系统受累相关的严重并发症。1例中,小肠受累伴有功能性梗阻。另外2例患者,食管受累进展为食管下端严重狭窄。因此,这种硬皮病形式的公认良性性质必须受到质疑。