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优化用于磁神经图和磁肌图应用的NV磁力测量法。

Optimizing NV magnetometry for Magnetoneurography and Magnetomyography applications.

作者信息

Zhang Chen, Zhang Jixing, Widmann Matthias, Benke Magnus, Kübler Michael, Dasari Durga, Klotz Thomas, Gizzi Leonardo, Röhrle Oliver, Brenner Philipp, Wrachtrup Jörg

机构信息

Institute of Physics, University of Stuttgart, Stuttgart, Germany.

Quantum Technology R&D Center, Beijing Automation Control Equipment Institute, Beijing, China.

出版信息

Front Neurosci. 2023 Jan 12;16:1034391. doi: 10.3389/fnins.2022.1034391. eCollection 2022.

Abstract

Magnetometers based on color centers in diamond are setting new frontiers for sensing capabilities due to their combined extraordinary performances in sensitivity, bandwidth, dynamic range, and spatial resolution, with stable operability in a wide range of conditions ranging from room to low temperatures. This has allowed for its wide range of applications, from biology and chemical studies to industrial applications. Among the many, sensing of bio-magnetic fields from muscular and neurophysiology has been one of the most attractive applications for NV magnetometry due to its compact and proximal sensing capability. Although SQUID magnetometers and optically pumped magnetometers (OPM) have made huge progress in Magnetomyography (MMG) and Magnetoneurography (MNG), exploring the same with NV magnetometry is scant at best. Given the room temperature operability and gradiometric applications of the NV magnetometer, it could be highly sensitive in the -range even without magnetic shielding, bringing it close to industrial applications. The presented work here elaborates on the performance metrics of these magnetometers to the state-of-the-art techniques by analyzing the sensitivity, dynamic range, and bandwidth, and discusses the potential benefits of using NV magnetometers for MMG and MNG applications.

摘要

基于金刚石中色心的磁力计因其在灵敏度、带宽、动态范围和空间分辨率方面的卓越综合性能,以及在从室温到低温的广泛条件下的稳定可操作性,正在为传感能力开辟新的前沿领域。这使其在从生物学和化学研究到工业应用等广泛领域得到应用。其中,由于其紧凑和近端传感能力,对肌肉和神经生理学产生的生物磁场进行传感一直是氮空位(NV)磁力测量最具吸引力的应用之一。尽管超导量子干涉仪(SQUID)磁力计和光泵磁力计(OPM)在肌磁图(MMG)和磁神经图(MNG)方面取得了巨大进展,但利用NV磁力测量进行同样的探索充其量也很少。鉴于NV磁力计的室温可操作性和梯度测量应用,即使没有磁屏蔽,它在特定范围内也可能具有高灵敏度,使其接近工业应用。本文通过分析灵敏度、动态范围和带宽,阐述了这些磁力计相对于最新技术的性能指标,并讨论了在MMG和MNG应用中使用NV磁力计的潜在益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8617/9885266/fb1b74747f1b/fnins-16-1034391-g0001.jpg

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