Department of Urology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC.
Department of Urology, College of Medicine and Shu-Tien Urological Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2023 Mar 1;86(3):295-299. doi: 10.1097/JCMA.0000000000000857. Epub 2023 Jan 23.
The aim of this study was to analyze the risk factors for hemorrhagic complications in patients who underwent robotic-assisted partial nephrectomy.
We retrospectively reviewed the records of 260 patients who underwent robotic-assisted partial nephrectomy. Hemorrhagic complications were defined as bleeding, hematoma, or arteriovenous fistula requiring hemostatic medication, blood transfusion, or therapeutic intervention. Hemorrhagic complications were graded according to the modified Clavien classification system, and the hemorrhagic complication group comprised only those complications with Clavien grade II or higher. Thereafter, we investigated the presence of any relevant association between perioperative factors and hemorrhagic complications.
Of 260 patients included in the study, 32 (12.3%) had hemorrhagic complications. The postoperative hemoglobin level was significantly lower in the hemorrhagic complication group than in the group without complications. The hemorrhagic complication group had significantly more essential blood loss and a significantly longer length of hospital stay. In the univariate analysis, type 2 diabetes mellitus, Radius-scores tumor size as maximal diameter exophytic/endophytic properties of the tumor nearness of the deepest portion of the tumor to the collecting system or renal sinus anterior (a)/posterior (p) descriptor location relative to the polar line., sum of the renal size plus renal sinus involvement in the PADUA score is a simple anatomical system that can be used to predict the risk of surgical and medical perioperative complications in patients undergoing open NSS, prolonged console time (>180 minutes), prolonged warm ischemic time (>25 minutes), and method of pedicle control were statistically significant risk factors. In the multivariate logistic regression analysis, warm ischemic time >25 minutes was the only significant risk factor for hemorrhagic complications (odds ratio, 3.51; 95% confidence interval, 1.28-9.59; p = 0.01).
Patients who undergo robotic-assisted partial nephrectomy with a warm ischemic time >25 minutes are significantly more likely to have hemorrhagic complications and should hence receive careful perioperative follow-up.
本研究旨在分析接受机器人辅助部分肾切除术患者发生出血并发症的风险因素。
我们回顾性分析了 260 例接受机器人辅助部分肾切除术患者的病历。出血并发症定义为需要止血药物、输血或治疗干预的出血、血肿或动静脉瘘。出血并发症根据改良 Clavien 分级系统进行分级,出血并发症组仅包括 Clavien 分级 II 级或更高的并发症。然后,我们研究了围手术期因素与出血并发症之间是否存在任何相关关联。
在纳入研究的 260 例患者中,32 例(12.3%)发生出血并发症。出血并发症组术后血红蛋白水平明显低于无并发症组。出血并发症组的术中失血量明显更多,住院时间明显更长。在单因素分析中,2 型糖尿病、肿瘤大小的 Radius-scores、肿瘤外生/内生性质、肿瘤最深部与集合系统或肾窦前(a)/后(p)描述符的距离、PADUA 评分中肾大小加肾窦受累的总和是一种简单的解剖系统,可用于预测接受开放式 NSS 的患者手术和围手术期并发症的风险,控制台时间延长(>180 分钟)、热缺血时间延长(>25 分钟)和蒂控制方法是统计学上显著的风险因素。在多因素逻辑回归分析中,热缺血时间>25 分钟是出血并发症的唯一显著危险因素(优势比,3.51;95%置信区间,1.28-9.59;p=0.01)。
热缺血时间>25 分钟的机器人辅助部分肾切除术患者发生出血并发症的风险显著增加,因此应接受仔细的围手术期随访。