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本文引用的文献

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Timing, incidence and management of delayed bleeding after partial nephrectomy in patients at risk for recurrent, bilateral, multifocal renal tumors.复发性、双侧、多灶性肾肿瘤风险患者部分肾切除术后迟发性出血的时间、发生率和处理。
Urol Oncol. 2024 Jul;42(7):222.e1-222.e7. doi: 10.1016/j.urolonc.2024.03.004. Epub 2024 Apr 12.
2
Surgical Trends and Complications in Partial and Radical Nephrectomy: Results from the GRAND Study.部分肾切除术和根治性肾切除术的手术趋势及并发症:GRAND研究结果
Cancers (Basel). 2023 Dec 24;16(1):97. doi: 10.3390/cancers16010097.
3
Dynamics and ecological reassembly of the human gut microbiome and the host metabolome in response to prolonged fasting.长时间禁食后人类肠道微生物群和宿主代谢组的动态变化与生态重组
Front Microbiol. 2023 Oct 3;14:1265425. doi: 10.3389/fmicb.2023.1265425. eCollection 2023.
4
Efficacy and safety of prolonged water fasting: a narrative review of human trials.长期禁食水的疗效和安全性:人体试验的叙述性综述。
Nutr Rev. 2024 Apr 12;82(5):664-675. doi: 10.1093/nutrit/nuad081.
5
Risk factors for hemorrhagic complications following robotic-assisted partial nephrectomy.机器人辅助部分肾切除术出血并发症的危险因素。
J Chin Med Assoc. 2023 Mar 1;86(3):295-299. doi: 10.1097/JCMA.0000000000000857. Epub 2023 Jan 23.
6
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Eur Urol. 2022 Nov;82(5):529-542. doi: 10.1016/j.eururo.2022.08.019. Epub 2022 Sep 10.
7
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Int Braz J Urol. 2022 Jul-Aug;48(4):625-636. doi: 10.1590/S1677-5538.IBJU.2021.0095.
8
POSTOPERATIVE HEMORRHAGE AS A COMPLICATION OF A PARTIAL NEPHRECTOMY: FREQUENCY, FEATURES AND MANAGEMENT.部分肾切除术术后出血并发症:频率、特征和处理。
Georgian Med News. 2021 Apr(313):12-20.
9
Effects of preoperative oral carbohydrate on postoperative discomfort in patients undergoing elective surgery: a meta-analysis of randomized controlled trials.择期手术患者术前口服碳水化合物对术后不适的影响:随机对照试验的荟萃分析。
Langenbecks Arch Surg. 2021 Jun;406(4):993-1005. doi: 10.1007/s00423-021-02110-2. Epub 2021 Feb 25.
10
Prolonged preoperative fasting induces postoperative insulin resistance by ER-stress mediated Glut4 down-regulation in skeletal muscles.长时间术前禁食通过内质网应激介导的骨骼肌 Glut4 下调诱导术后胰岛素抵抗。
Int J Med Sci. 2021 Jan 11;18(5):1189-1197. doi: 10.7150/ijms.52701. eCollection 2021.

术前禁食时间对接受部分肾切除术患者的影响及术后出血危险因素分析

The impact of preoperative fasting time on patients undergoing partial nephrectomy and analysis of risk factors for postoperative hemorrhage.

作者信息

Wang Chunji, Cui Jiazhao, Gao Zihui

机构信息

Department of Urology, Peking University First Hospital - MiYun Hospital, Beijing, China.

出版信息

Front Surg. 2024 Oct 3;11:1474910. doi: 10.3389/fsurg.2024.1474910. eCollection 2024.

DOI:10.3389/fsurg.2024.1474910
PMID:39421407
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11484038/
Abstract

OBJECTIVE

This study investigates the impact of preoperative fasting time on patients undergoing partial nephrectomy and analyzes the risk factors for postoperative hemorrhage to provide clinical reference for physicians treating patients undergoing partial nephrectomy.

METHODS

A retrospective analysis was conducted on 74 patients who underwent partial nephrectomy for renal tumors between January 2022 and March 2024. Baseline and perioperative data were collected. The effects of long-term and short-term preoperative fasting on patients undergoing partial nephrectomy were compared. Additionally, univariate and multivariate logistic regression analyses were performed to identify risk factors for hemorrhagic complications following partial nephrectomy.

RESULTS

Among the patients in this study, 26 (35.14%) underwent short-term preoperative fasting, while 48 (64.86%) underwent long-term preoperative fasting. The hemoglobin difference in the short-term fasting group was 21.08 ± 12.44 ml, compared to 13.65 ± 11.69 ml in the long-term fasting group, showing a statistically significant difference ( = 0.020). Differences in serum calcium ( = 0.003), serum magnesium ( = 0.031), and serum phosphorus ( = 0.001) between the short-term and long-term fasting groups were also statistically significant. Univariate and multivariate regression analyses identified the type of surgery ( = 0.050) and preoperative fasting time ( < 0.001) as independent risk factors for postoperative hemorrhage following partial nephrectomy.

CONCLUSION

Patients undergoing partial nephrectomy with short-term preoperative fasting experience a more significant decrease in hemoglobin compared to those with long-term fasting. The type of surgery and preoperative fasting time are independent risk factors for postoperative hemorrhage in patients undergoing partial nephrectomy.

摘要

目的

本研究探讨术前禁食时间对接受部分肾切除术患者的影响,并分析术后出血的危险因素,为治疗接受部分肾切除术患者的医生提供临床参考。

方法

对2022年1月至2024年3月期间接受肾肿瘤部分肾切除术的74例患者进行回顾性分析。收集基线和围手术期数据。比较术前长期和短期禁食对接受部分肾切除术患者的影响。此外,进行单因素和多因素逻辑回归分析,以确定部分肾切除术后出血并发症的危险因素。

结果

本研究中的患者中,26例(35.14%)接受了短期术前禁食,而48例(64.86%)接受了长期术前禁食。短期禁食组的血红蛋白差异为21.08±12.44ml,而长期禁食组为13.65±11.69ml,差异具有统计学意义(=0.020)。短期和长期禁食组之间的血清钙(=0.003)、血清镁(=0.031)和血清磷(=0.001)差异也具有统计学意义。单因素和多因素回归分析确定手术类型(=0.050)和术前禁食时间(<0.001)为部分肾切除术后出血的独立危险因素。

结论

与长期禁食的患者相比,接受部分肾切除术且术前短期禁食的患者血红蛋白下降更为显著。手术类型和术前禁食时间是接受部分肾切除术患者术后出血的独立危险因素。