Clin Nucl Med. 2023 Apr 1;48(4):339-341. doi: 10.1097/RLU.0000000000004578. Epub 2023 Jan 20.
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma with a high rate of metastasis and mortality. We present 68 Ga-DOTATATE PET/CT and 68 Ga-pentixiafor PET/CT findings of MCC in a 62-year-old man. Both 68 Ga-DOTATATE PET/CT and 68 Ga-pentixiafor PET/CT revealed increased radioactive uptake of lesions in the scan range. Compared with 68 Ga-DOTATATE PET/CT, the lesions showed higher uptake in 68 Ga-pentixiafor PET/CT. Our case showed that 68 Ga-pentixiafor might be a promising radiotracer in the evaluation of MCC.
默克尔细胞癌（Merkel cell carcinoma，MCC）是一种侵袭性神经内分泌癌，转移率和死亡率均较高。我们展示了一例 62 岁男性 MCC 的 68 Ga-DOTATATE PET/CT 和 68 Ga-pentixiafor PET/CT 表现。68 Ga-DOTATATE PET/CT 和 68 Ga-pentixiafor PET/CT 均显示扫描范围内病变的放射性摄取增加。与 68 Ga-DOTATATE PET/CT 相比，68 Ga-pentixiafor PET/CT 中病变的摄取更高。本病例表明，68 Ga-pentixiafor 可能是评估 MCC 的一种很有前途的放射性示踪剂。
