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双侧腮腺和颌下腺朗格汉斯细胞组织细胞增生症:18F-FDG PET/CT 的表现。

Langerhans Cell Histiocytosis of Bilateral Parotid and Submandibular Glands: Findings on 18F-FDG PET/CT.

机构信息

From the Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Clin Nucl Med. 2023 Apr 1;48(4):e200-e201. doi: 10.1097/RLU.0000000000004569. Epub 2023 Jan 14.

Abstract

Langerhans cell histiocytosis is a disorder of the mononuclear phagocytic system. Virtually any organ can be involved, the bone, skin, lungs, and pituitary gland being the most common. We describe the case of a 30-year-old man who presented with painless neck swelling. 18 F-FDG PET/CT showed bilateral bulky parotid and submandibular glands with increased metabolic activity. Histopathology confirmed the diagnosis of Langerhans cell histiocytosis. To our knowledge, there has been no description of 18 F-FDG PET/CT findings in Langerhans cell histiocytosis of salivary glands in literature. We aim to aid in the diagnosis and management of this rare presentation.

摘要

朗格汉斯细胞组织细胞增生症是一种单核吞噬细胞系统的疾病。几乎任何器官都可能受到影响,最常见的是骨骼、皮肤、肺部和垂体。我们描述了一名 30 岁男性的病例,他表现为无痛性颈部肿胀。18F-FDG PET/CT 显示双侧腮腺和颌下腺肿大,代谢活性增高。组织病理学证实了朗格汉斯细胞组织细胞增生症的诊断。据我们所知,在文献中尚未有关于唾液腺朗格汉斯细胞组织细胞增生症的 18F-FDG PET/CT 表现的描述。我们旨在帮助诊断和管理这种罕见的表现。

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