高血压与职业性噪声暴露对双耳高频听力损失的联合效应：一项大型横断面研究的证据。

The Combined Effect of Elevated Blood Pressure and Occupational Noise Exposure on Bilateral High-Frequency Hearing Loss: Evidence From a Large Sample Cross-sectional Study.

机构信息

From the Chongqing Center for Disease Control and Prevention, Chongqing, People's Republic of China.

出版信息

J Occup Environ Med. 2023 Apr 1;65(4):e219-e226. doi: 10.1097/JOM.0000000000002783.

DOI:10.1097/JOM.0000000000002783

PMID:36728160

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10090378/

Abstract

BACKGROUND

Combined effect of elevated blood pressure and occupational noise exposure on hearing loss have rarely been evaluated among Chinese population.

METHODS

This cross-sectional study was conducted in 242,811 participants. Logistic regression model was performed to estimate the independent and combined associations.

RESULTS

Compared with participants without occupational noise exposure, the risk of bilateral high-frequency hearing loss (BHFHL) was significantly higher for noise exposure 10 years or more (odds ratio [OR] = 1.29, 95% confidence interval [95% CI] = 1.23-1.35). Compared with no hypertension, participants with grade 1 hypertension had higher risk of BHFHL in all age groups (OR, 1.14; 95% CI, 1.09-1.20). As to the combined effect, the highest BHFHL risk was found in males (OR, 1.51; 95% CI, 1.37-1.67), especially among participants with grade 1 hypertension older than 50 years (OR, 1.65; 95% CI, 1.46-1.88).

CONCLUSIONS

Elevated blood pressure may synergistically influence hearing loss combined with occupational noise exposure.

摘要

背景

在中国人群中，很少有研究评估血压升高和职业性噪声暴露对听力损失的综合影响。

方法

本横断面研究纳入了 242811 名参与者。采用 logistic 回归模型来评估独立和联合效应。

结果

与无职业性噪声暴露的参与者相比，噪声暴露 10 年及以上者发生双侧高频听力损失（BHFHL）的风险显著升高（比值比[OR] = 1.29，95%置信区间[95%CI] = 1.23-1.35）。与无高血压相比，所有年龄段的 1 级高血压患者均有更高的 BHFHL 风险（OR，1.14；95%CI，1.09-1.20）。对于联合效应，男性的 BHFHL 风险最高（OR，1.51；95%CI，1.37-1.67），尤其是 50 岁以上的 1 级高血压患者（OR，1.65；95%CI，1.46-1.88）。