Department of Occupational Disease Prevention and Control, Chengdu Municipal Center for Disease Control and Prevention, Chengdu, Sichuan, China.
Department of AIDS/STD Control and Prevention, Chengdu High-tech Center for Disease Control and Prevention, Chengdu, Sichuan, China.
PLoS One. 2019 Sep 5;14(9):e0222135. doi: 10.1371/journal.pone.0222135. eCollection 2019.
To investigate the association of bilateral high-frequency hearing loss (BHFHL) with blood pressure and hypertension among occupational noise exposed workers.
Occupational noise exposed workers were enrolled in 2017 from the occupational diseases survey of Chengdu. BHFHL was classified as normal, mild, or high by the bilateral high-frequency tone average. Linear regression model was used to assess the effects of occupational noise exposure time and BHFHL on blood pressure. Logistic regression model was performed to estimate hypertension risk odds ratios (ORs) associated to occupational noise exposure time and BHFHL.
Increasing years of occupational noise exposure and BHFHL were significantly associated with systolic and diastolic blood pressure increase (all P<0.001). The lineal trend was only significant in males, with adjusted ORs for hypertension gradually increasing with increasing years of occupational noise exposure (P<0.001). Furthermore, subjects having mild and high BHFHL had a higher hypertension risk of 34% and 281%, respectively (both P<0.001). Dose-response relationship between BHFHL and hypertension was found in both males and females.
Occupational noise exposure was positively associated with blood pressure levels and hypertension risk.
探讨职业噪声暴露工人双侧高频听力损失（BHFHL）与血压和高血压的关系。
2017 年，我们从成都职业病调查中招募了职业噪声暴露工人。通过双侧高频平均音调将 BHFHL 分为正常、轻度或重度。线性回归模型用于评估职业噪声暴露时间和 BHFHL 对血压的影响。采用 logistic 回归模型估计与职业噪声暴露时间和 BHFHL 相关的高血压风险比值比（OR）。
职业噪声暴露年限和 BHFHL 的增加与收缩压和舒张压的升高显著相关（均 P<0.001）。线性趋势仅在男性中显著，调整后的 OR 值随着职业噪声暴露年限的增加而逐渐升高（P<0.001）。此外，轻度和重度 BHFHL 的受试者患高血压的风险分别增加了 34%和 281%（均 P<0.001）。在男性和女性中均发现了 BHFHL 与高血压之间的剂量-反应关系。
职业噪声暴露与血压水平和高血压风险呈正相关。
