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人工耳蜗植入术后短期生活质量变化的预测因素。

Predictors of Short-Term Changes in Quality of Life after Cochlear Implantation.

机构信息

Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, St Louis, Missouri.

出版信息

Otol Neurotol. 2023 Mar 1;44(3):e146-e154. doi: 10.1097/MAO.0000000000003805. Epub 2023 Jan 14.

Abstract

OBJECTIVE

This study aimed 1) to measure the effect of cochlear implantation on health-related quality of life (HR-QOL) using the Cochlear Implant Quality of Life (CIQOL) questionnaire and 2) to determine audiologic, demographic, and non-CI/hearing-related QOL factors influencing the CIQOL.

STUDY DESIGN

Prospective observational study.

SETTING

Tertiary referral center.

PATIENTS AND INTERVENTIONS

Thirty-seven adult patients with sensorineural hearing loss undergoing cochlear implantation.

MAIN OUTCOME MEASURES

CIQOL-global score preimplantation and 6 months postimplantation. Physical function score as measured by the short-form survey, audiologic, and demographic variables.

RESULTS

CIQOL showed significant improvement from preimplantation to 6 months postactivation with a mean difference of 14.9 points (95% confidence interval, 11.3 to 18.5, p < 0.0001). Improvement in CIQOL (ΔCIQOL) correlated linearly with age ( r = -0.49, p = 0.001) and improvement in speech perception testing ( r = 0.63, p < 0.0001). Multivariate modeling using age and change in consonant-vowel nucleus-consonant (CNC) score explained 46% of the variability measured by the ΔCIQOL-global score.

CONCLUSIONS

Nearly all CI recipients achieve significant gains for all domains as measured by the CIQOL. However, younger patients and those with a greater improvement in speech perception performance (CNC) are more likely to achieve a greater CIQOL benefit. Results here suggest the importance of considering preoperative CIQOL and speech perception measures when evaluating predictors of HR-QOL.

摘要

目的

本研究旨在:1)使用人工耳蜗植入生活质量问卷(CIQOL)评估人工耳蜗植入对健康相关生活质量(HR-QOL)的影响;2)确定影响 CIQOL 的听力学、人口统计学和非 CI/听力相关 QOL 因素。

研究设计

前瞻性观察性研究。

地点

三级转诊中心。

患者和干预措施

37 名成人感音神经性听力损失患者行人工耳蜗植入术。

主要观察指标

植入前和植入后 6 个月的 CIQOL-全球评分。身体功能评分,采用简短式健康调查量表测量,以及听力学和人口统计学变量。

结果

CIQOL 在植入后 6 个月与植入前相比有显著提高,平均差异为 14.9 分(95%置信区间,11.3 至 18.5,p < 0.0001)。CIQOL 的改善(ΔCIQOL)与年龄呈线性相关(r = -0.49,p = 0.001),与言语感知测试的改善呈正相关(r = 0.63,p < 0.0001)。使用年龄和辅音-元音-辅音核(CNC)评分变化进行多元建模,解释了 ΔCIQOL-全球评分的 46%的可变性。

结论

几乎所有人工耳蜗植入者在 CIQOL 测量的所有领域都获得了显著的改善。然而,年龄较小的患者和言语感知表现(CNC)改善较大的患者更有可能获得更大的 CIQOL 获益。这些结果表明,在评估 HR-QOL 的预测因素时,考虑术前 CIQOL 和言语感知测量结果非常重要。

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