Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI.
Department of Oral Pathology, Radiology and Medicine, University of Iowa College of Dentistry, Iowa City, IA.
Am J Dermatopathol. 2023 Mar 1;45(3):e17-e21. doi: 10.1097/DAD.0000000000002382. Epub 2023 Jan 10.
Rhabdomyosarcoma (RMS) is one of the most common soft tissue sarcomas in children. This lesion is classically included in the generic group of "small round blue cell tumors" along with other entities that share similar microscopic features. Although the head and neck region is a frequent site for primary tumors, cutaneous metastases of RMS involving this anatomical location are rare in the pediatric population. We report a case of a 12-year old girl previously diagnosed with a primary alveolar RMS involving the left maxillary sinus, presenting with a metastatic lesion on the skin of the left temple area. Along with a brief review of the previous case reports on the topic, we highlight the initial immunohistochemistry panel useful for diagnosing this tumor.
横纹肌肉瘤（RMS）是儿童中最常见的软组织肉瘤之一。这种病变通常被归入“小圆蓝细胞肿瘤”的通用组中，与具有相似微观特征的其他实体一起。尽管头颈部是原发性肿瘤的常见部位，但儿童人群中 RMS 的皮肤转移累及该解剖部位较为罕见。我们报告了一例 12 岁女孩，她曾被诊断出患有左上颌窦原发性肺泡 RMS，现左侧太阳穴皮肤出现转移病变。我们简要回顾了该主题的先前病例报告，并强调了用于诊断该肿瘤的初始免疫组织化学小组。
