Sancaktepe Sehit Prof Dr Ilhan Varank Training and Research Hospital, Sancaktepe, İstanbul.
Clin Neuropharmacol. 2023;46(2):82-84. doi: 10.1097/WNF.0000000000000535. Epub 2022 Dec 27.
Botulinum toxin type A is widely used for the treatment of spasticity, focal dystonia, hemifacial spasm, hyperhidrosis, strabismus, chronic migraine, and also cosmetic purposes. Therapeutic use is commonly effective and safe. However, if toxin enters the vascular space and gets through to peripheral cholinergic nerve terminals, it may lead to iatrogenic botulism.
We presented a patient who is diagnosed as iatrogenic botulism and treated with antitoxin at the 15th day of the exposure.
After the antitoxin administration, dramatical response to the treatment was observed.
In this report, we want to evaluate a new case of iatrogenic botulism and emphasize the importance of antitoxin administration regardless the timing of the exposure for patients with progressing paralysis.
肉毒毒素 A 广泛用于治疗痉挛、局灶性肌张力障碍、半面痉挛、多汗症、斜视、慢性偏头痛，也用于美容目的。治疗用途通常是有效且安全的。然而，如果毒素进入血管空间并到达周围胆碱能神经末梢，可能导致医源性肉毒中毒。
我们介绍了一位患者，他在暴露后第 15 天被诊断为医源性肉毒中毒，并接受了抗毒素治疗。
抗毒素给药后，观察到治疗效果显著。
在本报告中，我们想评估一例新的医源性肉毒中毒病例，并强调无论暴露时间如何，对于进展性瘫痪的患者，给予抗毒素的重要性。
