肉毒杆菌毒素A治疗后发生的医源性肉毒中毒：一例病例报告及文献复习
Iatrogenic botulism after the therapeutic use of botulinum toxin-A: a case report and review of the literature.
作者信息
Ghasemi Majid, Norouzi Rasul, Salari Mehri, Asadi Bahador
机构信息
Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran.
出版信息
Clin Neuropharmacol. 2012 Sep-Oct;35(5):254-7. doi: 10.1097/WNF.0b013e31826248b8.
PMID:22986799
Abstract
Local injection of botulinum toxin-A is an accepted treatment for hyperhidrosis. We report 2 cases of primary hyperhidrosis who developed iatrogenic botulism after the therapeutic dose of onabotulinumtoxinA (Botox). This case report highlights the necessity of clinicians having sufficient information of potentially adverse effects, optimal dose, and correct preparation and injection of botulinum toxin-A.
摘要
局部注射A型肉毒毒素是多汗症的一种公认治疗方法。我们报告了2例原发性多汗症患者，在接受治疗剂量的A型肉毒杆菌毒素（保妥适）后发生了医源性肉毒中毒。本病例报告强调了临床医生掌握有关潜在不良反应、最佳剂量以及正确配制和注射A型肉毒毒素的充分信息的必要性。
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