石棉沉着病患者的合并症及死亡原因

Comorbidities and Causes of Death of Patients With Asbestosis.

作者信息

Keskitalo Eerika, Salonen Johanna, Nurmi Hanna, Vähänikkilä Hannu, Kaarteenaho Riitta

机构信息

From the ResearchUnit of InternalMedicine, University of Oulu, Oulu, Finland (E.K., J.S., R.K.); Center of Internal and Respiratory Medicine, Medical Research Center (MRC) Oulu, Oulu, Finland (E.K., J.S., R.K.); Division of Respiratory Medicine, Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (H.N.); Center of Medicine and Clinical Research, Department of Respiratory Medicine, Kuopio University Hospital, Kuopio, Finland (H.N.); Northern Finland Birth Cohorts, Arctic Biobank, Infrastructure for Population studies, Faculty of Medicine, University of Oulu, Oulu, Finland (H.V.).

出版信息

J Occup Environ Med. 2023 Apr 1;65(4):349-353. doi: 10.1097/JOM.0000000000002777. Epub 2022 Dec 23.

DOI:10.1097/JOM.0000000000002777

PMID:36728947

Abstract

OBJECTIVE

Comorbidities are common and affect the prognosis of patients with interstitial lung diseases, but few previous studies have investigated patients with asbestosis.

METHODS

We collected comorbidities and death causes of 116 patients with asbestosis treated in Oulu University Hospital. Causes of death were confirmed by autopsy in 68% of the cases.

RESULTS

The most common comorbidities of asbestosis patients were pleural plaques (96%) and coronary artery disease (CAD; 67%). The prevalence of rheumatoid arthritis was 8.6%. The most common underlying causes of death were asbestosis (36%), CAD (24%), and lung cancer (LC) (10%). CAD and LC were associated with shorter survival in adjusted analyses.