Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education; Yunnan Research & Development Center for Natural Products; School of Chemical Science and Technology and School of Medicine, Yunnan University, Kunming 650091, China.
State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming 650091, China.
J Asian Nat Prod Res. 2023 Oct;25(10):968-975. doi: 10.1080/10286020.2023.2173587. Epub 2023 Feb 2.
Two new compounds, including a norsesquiterpenoid, annuionone H (), and a quassinoid, picraqualide G (), along with eleven known compounds (), were isolated from the twigs and leaves of . Comprehensive spectroscopic analyses and NMR calculation with DP4+ analysis were used to identify their structures. Moreover, of all these compounds, compound showed a week inhibition rate in the anti-inflammatory screening results against mouse macrophage J774A.1 cell.
从羊角拗的嫩枝和叶中分离得到了两个新化合物,包括一个新的降二萜类化合物 annuionone H () 和一个新的三萜类化合物 picraqualide G (),以及 11 个已知化合物 ()。通过综合光谱分析和 DP4+ 分析的 NMR 计算确定了它们的结构。此外,在抗炎筛选实验中,所有这些化合物中,化合物 对小鼠巨噬细胞 J774A.1 细胞的抑制率较弱。