Northeast Ohio Medical University, Rootstown, OH.
Dermatology, Surgery, and Cosmetics of Northeast Ohio, Medina, OH; and.
Am J Dermatopathol. 2023 Mar 1;45(3):196-200. doi: 10.1097/DAD.0000000000002355. Epub 2022 Dec 7.
Nevus sebaceus (NS) is a cutaneous hamartoma typically found on the head and neck, with a prevalence of 0.3% in newborns. Most NS are quiescent; however, benign and malignant lesions have been reported to arise within these nevi. Malignant transformation is not common but mainly includes basal cell carcinoma and squamous cell carcinoma. Malignant melanoma arising in NS is exceedingly rare, with only 2 previously documented cases. In this article, we report the first case of malignant melanoma arising in a NS in a 68-year-old man in the United States.
皮脂腺痣（NS）是一种常见于头颈部的皮肤错构瘤，新生儿中的发病率为 0.3%。大多数 NS 处于静止状态；然而，已有良性和恶性病变在这些痣中发生的报道。恶性转化并不常见，但主要包括基底细胞癌和鳞状细胞癌。NS 中发生的恶性黑色素瘤极为罕见，仅有 2 例先前有文献记载。本文报道了首例发生于美国 68 岁男性 NS 中的恶性黑色素瘤。
