Cicek Ali Fuat, Aykan Andac, Yapici Abdulkerim, Gamsizkan Mehmet, Ozturk Serdar, Demiriz Murat
Department of Pathology, Gülhane Military Medical Academy, Ankara, Turkey.
Indian J Pathol Microbiol. 2015 Oct-Dec;58(4):534-6. doi: 10.4103/0377-4929.168885.
Nevus sebaceus (NS) is a congenital, benign, hamartomatous lesion and it is possible to see several benign or malignant tumors accompanying it. One of these is the poroma, which is very rare, and has only been reported twice before, in the English literature. In this paper, we presented two new cases of NS. One of them was a 40-year-old male who presented with a congenital skin lesion on his temporoparietal region. This lesion was composed of four different lesions, including NS, poroma, basal cell carcinoma (BCC), and verruca vulgaris. The second patient was a 41-year-old male presenting with a yellow-brown patch on the scalp. This lesion was comprised of NS and BCC. In addition to these presentations, we discussed the differential diagnosis between BCC and trichoblastoma, both of which are likely to be seen with NS. For this purpose, we recommended an immunohistological panel, which may be useful for differentiating these two morphologically similar lesions.
皮脂腺痣(NS)是一种先天性良性错构瘤性病变,可能会伴有几种良性或恶性肿瘤。其中之一是汗孔瘤,非常罕见,在英文文献中此前仅报道过两次。在本文中,我们展示了两例新的皮脂腺痣病例。其中一例是一名40岁男性,颞顶区有先天性皮肤病变。该病变由四种不同病变组成,包括皮脂腺痣、汗孔瘤、基底细胞癌(BCC)和寻常疣。第二例患者是一名41岁男性,头皮有黄褐色斑块。该病变由皮脂腺痣和基底细胞癌组成。除了这些病例展示,我们还讨论了基底细胞癌和毛发母细胞瘤之间的鉴别诊断,这两种肿瘤都可能与皮脂腺痣同时出现。为此,我们推荐了一组免疫组织化学检查,这可能有助于鉴别这两种形态相似的病变。