Samarawickrema W A, Laurence B R
Ann Trop Med Parasitol. 1978 Dec;72(6):561-5. doi: 10.1080/00034983.1978.11719361.
Analysis of log normal parasite densities of Wuchereria bancrofti in the mosquito Culex pipiens fatigans collected in the suburbs of Colombo, Sri Lanka, has shown a decreasing parasite load with age of infection. The median density of microfilarial intake in the natural population was 10.3, but this had decreased to 2.6 by the infective stage. Of the total microfilariae ingested, 51.9% were found in the thorax 12--17 hours after infection of the mosquitoes in the laboratory. Further decrease in parasite density during development could not be attributed to filarial mortality in the mosquito but could be accounted for by increasing mosquito mortality dependent on the density of parasite infection. Dissection of recently blood-fed house-resting mosquitoes gave a prevalence rate of 7% microfilarial carriers in the human population compared to a rate of 4% by routine blood-filming.
对在斯里兰卡科伦坡郊区采集的致倦库蚊体内班氏吴策线虫对数正态寄生虫密度的分析表明，随着感染时间的推移，寄生虫负荷呈下降趋势。自然种群中微丝蚴摄入的中位数密度为10.3，但到感染期时已降至2.6。在实验室感染蚊子12 - 17小时后，在摄入的全部微丝蚴中，51.9%位于胸部。发育过程中寄生虫密度的进一步降低不能归因于蚊子体内丝虫的死亡，而是可以由依赖寄生虫感染密度增加的蚊子死亡率来解释。解剖近期吸食人血后在室内停歇的蚊子发现，人群中微丝蚴携带者的患病率为7%，而常规血涂片检查的患病率为4%。
