Centre for Human Drug Research, Leiden, The Netherlands.
Leiden University Medical Center, Leiden, The Netherlands.
PLoS One. 2023 Feb 2;18(2):e0278300. doi: 10.1371/journal.pone.0278300. eCollection 2023.
Drivers should be aware of possible impairing effects of alcohol, medicinal substance, or fatigue on driving performance. Such effects are assessed in clinical trials, including a driving task or related psychomotor tasks. However, a choice between predicting tasks must be made. Here, we compare driving performance with on-the-road driving, simulator driving, and psychomotor tasks using the effect of sleep deprivation.
This two-way cross over study included 24 healthy men with a minimum driving experience of 3000km per year. Psychomotor tasks, simulated driving, and on-the-road driving were assessed in the morning and the afternoon after a well-rested night and in the morning after a sleep-deprived night. Driving behaviour was examined by calculating the Standard Deviation of Lateral Position (SDLP).
SDLP increased after sleep deprivation for simulated (10cm, 95%CI:6.7-13.3) and on-the-road driving (2.8cm, 95%CI:1.9-3.7). The psychomotor test battery detected effects of sleep deprivation in almost all tasks. Correlation between on-the-road tests and simulator SDLP after a well-rested night (0.63, p < .001) was not present after a night of sleep deprivation (0.31, p = .18). Regarding the effect of sleep deprivation on the psychomotor test battery, only adaptive tracking correlated with the SDLP of the driving simulator (-0.50, p = .02). Other significant correlations were related to subjective VAS scores.
The lack of apparent correlations and difference in sensitivity of performance of the psychomotor tasks, simulated driving and, on-the-road driving indicates that the tasks may not be interchangeable and may assess different aspects of driving behaviour.
驾驶员应意识到酒精、药物或疲劳对驾驶表现的可能影响。这些影响在临床试验中进行评估,包括驾驶任务或相关的心理运动任务。然而,必须在预测任务之间做出选择。在这里,我们比较了睡眠剥夺对驾驶表现、模拟驾驶和心理运动任务的影响。
这项两向交叉研究纳入了 24 名健康男性,他们每年至少有 3000 公里的驾驶经验。在一夜好眠后的上午和下午,以及一夜睡眠剥夺后的上午,评估了心理运动任务、模拟驾驶和道路驾驶。通过计算横向位置标准差(SDLP)来检查驾驶行为。
睡眠剥夺后,模拟驾驶(10cm,95%CI:6.7-13.3)和道路驾驶(2.8cm,95%CI:1.9-3.7)的 SDLP 增加。在一夜好眠后,心理运动测试几乎在所有任务中都检测到了睡眠剥夺的影响,但在一夜睡眠剥夺后,该测试与模拟驾驶 SDLP 之间的相关性(0.31,p=0.18)并不存在。关于睡眠剥夺对心理运动测试的影响,只有适应性跟踪与驾驶模拟器的 SDLP 相关(-0.50,p=0.02)。其他显著相关与主观 VAS 评分有关。
心理运动任务、模拟驾驶和道路驾驶的性能之间缺乏明显的相关性和敏感性差异表明,这些任务可能不可互换,可能评估驾驶行为的不同方面。