Departments of Pediatric Hematology.
Otolaryngology-Head and Neck Surgery.
J Pediatr Hematol Oncol. 2023 Jul 1;45(5):e628-e630. doi: 10.1097/MPH.0000000000002592. Epub 2022 Nov 15.
The posttransplant lymphoproliferative disease is a severe cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation. Central Nervous System involvement in EBV-related PTLD is rare, and there is no standard treatment recommendation. We present our patient and discuss other previously reported cases of EBV-associated PTLD with CNS involvement.
移植后淋巴组织增生性疾病是异基因造血干细胞移植后发病率和死亡率的严重原因。 EBV 相关的 PTLD 累及中枢神经系统的情况较为罕见,也没有标准的治疗推荐。我们介绍了我们的患者,并讨论了其他先前报道的 EBV 相关的累及中枢神经系统的 PTLD 病例。