West Virginia University Eye Institute, Morgantown, West Virginia; and.
Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania.
Retin Cases Brief Rep. 2024 Mar 1;18(2):251-254. doi: 10.1097/ICB.0000000000001360. Epub 2022 Oct 29.
To present a case of extensive bilateral choroidal infarctions from multiple organ dysfunction syndrome and disseminated intravascular coagulation.
A retrospective case report. The medical and imaging records, including fundus photography, optical coherence tomography, fluorescein angiography, and visual fields, were reviewed.
A 49-year-old woman presented after a failed suicidal attempt from drug overdose. The patient was subsequently intubated for acute hypoxic respiratory failure with presumed septic shock from aspiration pneumonia while requiring exogenous adrenergic support. Her hospital course was further complicated by development of multiple organ dysfunction syndrome and disseminated intravascular coagulation. The patient complained of blurry vision in both eyes after regaining consciousness.
Fundus photography showed bilateral dot-blot hemorrhages and cotton wool spots followed by multiple areas of triangular granular pigmentation, consistent with choroidal infarcts. Fluorescein angiography revealed delayed patchy filling, followed by late staining. Optical coherence tomography showed diffuse thinning of the choroid with overlying retina pigment epithelium atrophy. Goldmann visual field displayed discrete areas of visual field deficits. At the most recent visit, the best-corrected final visual acuity remained 20/100 in the right eye and 20/30 in the left eye.
Disseminated intravascular coagulation has been associated with choroidal infarcts. We present a case of extensive bilateral choroidal infarction in a patient with combined disseminated intravascular coagulation and multiple organ dysfunction syndrome consistent with Amalric choroidal triangular sign.
报告一例由多器官功能障碍综合征和弥散性血管内凝血引起的广泛双侧脉络膜梗死病例。
回顾性病例报告。回顾了包括眼底照相、光相干断层扫描、荧光素血管造影和视野在内的医学和影像学记录。
一名 49 岁女性,因药物过量自杀未遂后就诊。患者随后因吸入性肺炎导致急性低氧性呼吸衰竭而被插管,并发疑似脓毒症性休克,需要外源性肾上腺素支持。她的住院过程进一步复杂化,出现多器官功能障碍综合征和弥散性血管内凝血。患者在恢复意识后主诉双眼视力模糊。
眼底照相显示双侧斑点状出血和棉絮斑,随后出现多个三角形颗粒状色素沉着区,符合脉络膜梗死。荧光素血管造影显示斑片状延迟填充,随后出现晚期染色。光相干断层扫描显示脉络膜弥漫性变薄,伴视网膜色素上皮萎缩。Goldmann 视野显示离散的视野缺损区域。在最近一次就诊时,右眼最佳矫正视力仍为 20/100,左眼为 20/30。
弥散性血管内凝血与脉络膜梗死有关。我们报告了一例广泛双侧脉络膜梗死病例,该患者合并弥散性血管内凝血和多器官功能障碍综合征,符合 Amalric 脉络膜三角形征。