Grover Casey, Sturgill Drew, Goldman Lee
From the Community Hospital of the Monterey Peninsula, Monterey, CA.
J Addict Med. 2023;17(2):219-221. doi: 10.1097/ADM.0000000000001047. Epub 2022 Aug 8.
Post-acute withdrawal syndrome is an underresearched topic that affects many patients with substance use disorders after the cessation of substance use. Post-acute withdrawal syndrome is exemplified by the occurrence of substance-specific withdrawal signs and symptoms lasting well past the known timeframe for acute withdrawal of a used substance. Post-acute withdrawal syndrome may also include signs and symptoms that are not substance specific that persist, evolve, or appear well past the expected acute withdrawal timeframe. Unfortunately, there is very little scientific literature on post-acute withdrawal syndrome. As a result of this, there are no diagnostic criteria for post-acute withdrawal syndrome, and there is no consensus on the proper name for the condition. We present a case of a 38-year-old man who developed post-acute withdrawal syndrome after treatment with buprenorphine for opioid use disorder and review the limited existing literature on post-acute withdrawal syndrome.
急性戒断后综合征是一个研究不足的课题,它影响着许多物质使用障碍患者在停止使用物质后的情况。急性戒断后综合征的特点是,物质特异性戒断体征和症状的出现持续时间远远超过已知的所使用物质急性戒断的时间范围。急性戒断后综合征还可能包括非物质特异性的体征和症状,这些症状在预期的急性戒断时间范围之后持续存在、演变或出现。不幸的是,关于急性戒断后综合征的科学文献非常少。因此,目前尚无急性戒断后综合征的诊断标准,对于该病症的恰当名称也没有达成共识。我们报告一例38岁男性在使用丁丙诺啡治疗阿片类物质使用障碍后出现急性戒断后综合征的病例,并回顾关于急性戒断后综合征的现有有限文献。