• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

A Geant4 shielding design for the first US carbon multi-ion hybrid synchrotron facility.

作者信息

Dougherty Jingjing M, Bolst David, Furutani Keith M, Guatelli Susanna, Liang Xiaoying, Rosenfeld Anatoly, Beltran Chris J

机构信息

Division of Medical Physics, Department of Radiation Oncology, Mayo Clinic, Jacksonville, Florida, United States of America.

Centre for Medical Radiation Physics, University of Wollongong, Wollongong, Australia.

出版信息

Phys Med Biol. 2023 Feb 28;68(5). doi: 10.1088/1361-6560/acb887.

DOI:10.1088/1361-6560/acb887
PMID:36731141
Abstract

The Mayo Clinic Florida Integrated Oncology Building will be the home of the first spot-scanning only carbon/proton hybrid therapy system by Hitachi, Ltd. It will provide proton beams up to kinetic energies of 230 MeV and carbon beams up to 430 MeV nfor clinical deployment. To provide adequate radiation protection, the Geant4 (v10.6) Monte Carlo toolkit was utilized to quantify the ambient dose equivalent at a 10 mm depth (*(10)) for photons and neutrons. To perform accurate calculations of the ambient dose equivalent, three-dimensional computer-aided design files of the entire planned facility were imported into Geant4, as well as certain particle system components such as the bending magnets, fast Faraday cup, and gantry. Particle fluence was scored using 60 cm diameter spheres, which were strategically placed throughout areas of interests. Analytical calculations were performed as first-pass design checks. Major shielding slabs were optimized using Geant4 simulations iteratively, with more than 20 alternative designs evaluated within Geant4. The 430 MeV ncarbon beams played the most significant role in concrete thickness Requirements. The primary wall thickness for the carbon fixed beam room is 4 meters. The presence of the proton gantry structure in the simulation caused the ambient dose equivalent to increase by around 67% at the maze entrance, but a decrease in the high energy beam transport corridor. All shielding primary and secondary goals for clinical operations were met per state regulation and national guidelines.

摘要

相似文献

1
A Geant4 shielding design for the first US carbon multi-ion hybrid synchrotron facility.
Phys Med Biol. 2023 Feb 28;68(5). doi: 10.1088/1361-6560/acb887.
2
Radiation shielding assessment of high-energy proton imaging at a proton therapy facility.高能质子成像在质子治疗设施中的辐射屏蔽评估。
Med Phys. 2022 Aug;49(8):5340-5346. doi: 10.1002/mp.15727. Epub 2022 Jun 6.
3
Shielding implications for secondary neutrons and photons produced within the patient during IMPT.在 IMPT 中,患者体内产生的次级中子和光子的屏蔽影响。
Med Phys. 2013 Jul;40(7):071701. doi: 10.1118/1.4807089.
4
A comprehensive Monte Carlo study of out-of-field secondary neutron spectra in a scanned-beam proton therapy gantry room.扫描束质子治疗机架室中外照射野次级中子能谱的综合蒙特卡罗研究。
Z Med Phys. 2021 May;31(2):215-228. doi: 10.1016/j.zemedi.2021.01.001. Epub 2021 Feb 20.
5
Neutron shielding for a new projected proton therapy facility: A Geant4 simulation study.新建质子治疗设施的中子屏蔽:一项Geant4模拟研究。
Phys Med. 2016 Dec;32(12):1862-1871. doi: 10.1016/j.ejmp.2016.12.003.
6
Neutron H*(10) inside a proton therapy facility: comparison between Monte Carlo simulations and WENDI-2 measurements.质子治疗设施内的中子H*(10):蒙特卡罗模拟与WENDI-2测量结果的比较。
Radiat Prot Dosimetry. 2014 Oct;161(1-4):417-21. doi: 10.1093/rpd/nct289. Epub 2013 Nov 19.
7
Analytical shielding calculations for a proton therapy facility.质子治疗设施的分析屏蔽计算。
Radiat Prot Dosimetry. 2008;131(2):167-79. doi: 10.1093/rpd/ncn136. Epub 2008 May 16.
8
Systematic out-of-field secondary neutron spectrometry and dosimetry in pencil beam scanning proton therapy.笔形束扫描质子治疗中的系统外野次级中子谱测量与剂量学研究。
Med Phys. 2017 May;44(5):1912-1920. doi: 10.1002/mp.12206. Epub 2017 Apr 20.
9
Neutrons from fragmentation of light nuclei in tissue-like media: a study with the GEANT4 toolkit.组织样介质中轻核裂变产生的中子:使用GEANT4工具包的一项研究。
Phys Med Biol. 2005 Dec 7;50(23):5493-507. doi: 10.1088/0031-9155/50/23/005. Epub 2005 Nov 8.
10
Evaluation of GATE-RTion (GATE/Geant4) Monte Carlo simulation settings for proton pencil beam scanning quality assurance.用于质子笔形束扫描质量保证的GATE-RTion(GATE/Geant4)蒙特卡罗模拟设置评估。
Med Phys. 2020 Nov;47(11):5817-5828. doi: 10.1002/mp.14481. Epub 2020 Oct 17.

引用本文的文献

1
The rationale for a carbon ion radiation therapy facility in Australia.在澳大利亚建设碳离子放射治疗设施的基本原理。
J Med Radiat Sci. 2024 Apr;71 Suppl 2(Suppl 2):59-76. doi: 10.1002/jmrs.744. Epub 2023 Dec 7.