利用区块链技术提高生物样本库中生物样本的安全性和可追溯性。

Increasing the security and traceability of biological samples in biobanks by blockchain technology.

作者信息

Ortiz-Lizcano María Isabel, Arias-Antunez Enrique, Hernández Bravo Ángel, Caminero María Blanca, Rojo Guillen Tomás, Nam Cha Syong Hyun

机构信息

Alpinia Technologies, Ciudad Real, Spain.

Departamento de Sistemas Informáticos, Escuela Superior de Ingeniería Informática de Albacete, Universidad de Castilla-La Mancha, Paseo de los Estudiantes s/n, Albacete 02071, Spain.

出版信息

Comput Methods Programs Biomed. 2023 Apr;231:107379. doi: 10.1016/j.cmpb.2023.107379. Epub 2023 Jan 27.

DOI:10.1016/j.cmpb.2023.107379

PMID:36731311

Abstract

BACKGROUND AND OBJECTIVE

One of the main tasks in a biobank consists in storing biological samples in a high-quality condition in order to future research. At moment, there exist many applications to manage a biobank. However, in general, these are web-based applications. In these web-based applications different tasks can be done. Among them, it is possible to remark the following: informed consent, confidentiality, non-profit, respect for quality and safety standards, including traceability of samples. In this paper, we describe a blockchain smart contract to ensure the traceability of the processes done in a biobank meaning a step forward to guarantee this traceability.

METHODS

Use of blockchain technology to improve security, integrity and traceability of the processes carried out in a biobank. In particular IBM Hyperledger Fabric.

RESULTS

As a result, a set of smart contracts have been developed describing the biobank processes.

CONCLUSIONS

Improvement of the security, integrity, and traceability of samples in biobanks.

摘要

背景与目的

生物样本库的主要任务之一是将生物样本以高质量状态保存，以供未来研究使用。目前，存在许多用于管理生物样本库的应用程序。然而，总体而言，这些都是基于网络的应用程序。在这些基于网络的应用程序中，可以完成不同的任务。其中，可以提及以下几点：知情同意、保密性、非营利性、对质量和安全标准的尊重，包括样本的可追溯性。在本文中，我们描述了一种区块链智能合约，以确保生物样本库中所执行流程的可追溯性，这意味着在保证这种可追溯性方面向前迈进了一步。