Rentsch W, Niederlag W, Foelske H, Wunderlich E, Schmidt P K
Laboratorium für bio-medizinische Elektronik, Pirna.
Z Gesamte Inn Med. 1987 Jul 15;42(14):386-9.
Of the parameters in consideration for control of physiological rate responsive pacing special interest is directed to stroke volume. In search of indirect parameters which are correlated to stroke volume it is demonstrated on principle that systolic time intervals could be used. From the relation ejection time versus pre-ejection time (LVET/PEP) which is known for its correlation to stroke volume a simple algorithm is derived which is based on the realization that PEP is related to the reciprocal of cardiac output. First investigations with patients demonstrated the possibility of the computation of heart rate from PEP only, with good physiological significance.
在考虑用于控制生理性频率应答起搏的参数时，特别关注每搏输出量。在寻找与每搏输出量相关的间接参数时，原则上证明了收缩期时间间期可被利用。从已知与每搏输出量相关的射血时间与射血前期时间的关系（左室射血时间/射血前期时间，LVET/PEP）中，得出了一个简单的算法，该算法基于射血前期时间与心输出量的倒数相关这一认识。对患者的初步研究表明，仅根据射血前期时间计算心率是可行的，且具有良好的生理学意义。
