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[滑膜针吸活检对风湿病诊断意义的随访研究]

[Catamnestic studies of the significance of synovial membrane needle biopsy for the diagnosis of rheumatic disease].

作者信息

Haas S, Schwenke R, Heidelmann G

机构信息

Funktionseinheit Stadtkrankenhaus Dr. Paul Kirchner Poliklinik, Radeberg.

出版信息

Z Gesamte Inn Med. 1987 Jul 15;42(14):397-401.

PMID:3673136
Abstract

By means of a catamnestic study diagnostic evidence, number of complications and examination-conditioned stress of the patient caused by needle biopsy of the synovial membrane were tested. 4-11 years after a blind biopsy of the synovial membrane carried out on account of rheumatological indication 80 patients (48 males, 32 females) were examined and the results of the preliminary examination and the secondary examination were compared with the findings of the needle biopsy of the synovial membrane. While the needle biopsy of the synovial membrane in rheumatoid arthritis has a high diagnostic value in comparison to clinical and paraclinical findings, in the histomorphological ascertainment of the uric arthritis the catamnestic study shows the limits of the method due to place-depending differences of the findings of the crystalline deposit in the synovial membrane. The number of complications of the investigation technique was insignificant and had no influence on the duration of the inability to work. As a highly specialised diagnostic method the blind biopsy of the synovial membrane may contribute to the clarification of problem cases in institutions with rheumatological profile without possibility of arthroscopy.

摘要

通过一项回顾性研究,对滑膜针吸活检的诊断证据、并发症数量以及检查引起的患者应激情况进行了检测。在因风湿病指征进行滑膜盲目活检4至11年后,对80例患者(48例男性,32例女性)进行了检查,并将初检和复检结果与滑膜针吸活检结果进行了比较。虽然类风湿性关节炎的滑膜针吸活检与临床和辅助检查结果相比具有较高的诊断价值,但在痛风性关节炎的组织形态学确诊中,回顾性研究显示,由于滑膜中结晶沉积物的发现存在部位差异,该方法存在局限性。检查技术的并发症数量微不足道,且对无法工作的持续时间没有影响。作为一种高度专业化的诊断方法,滑膜盲目活检可能有助于在没有关节镜检查条件的风湿病专科医院中对疑难病例进行诊断。

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