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儿童患者肢体长度差异外固定后摩根摩根菌致胫骨骨髓炎:病例报告及文献复习。

Tibial Osteomyelitis Caused by Morganella morganii After External Fixation for Limb Length Discrepancy in a Pediatric Patient: A Case Report and Literature Review.

机构信息

From the Baylor College of Medicine, Houston, TX (Mody-Bailey); the Oakland University William Beaumont School of Medicine, Rochester, MI (Ezeokoli) and the Department of Orthopaedics and Scoliosis Surgery, Texas Children's Hospital, Houston, TX (Ezeokoli, Dr. Hill).

出版信息

J Am Acad Orthop Surg Glob Res Rev. 2022 Dec 19;6(12). doi: 10.5435/JAAOSGlobal-D-22-00171. eCollection 2022 Dec 1.

Abstract

Morganella morganii is a facultative, anaerobic rod Gram-negative enteric bacterium. Few cases are documented of musculoskeletal infection. We present a case of a 9-year-old boy with osteomyelitis 1 year after index external fixation for leg length discrepancy. Our patient initially presented with wound drainage at his distal medial tibia fixation site but had negative radiographs. Initial antibiotic treatment failed after 1-month follow-up, and cultures revealed M. morganii. He underwent incision and drainage with external fixator removal, and the antibiotic regimen changed after a susceptibility panel. Symptoms were alleviated after 30 days with the new antibiotic regimen, and the patient was put back on his original schedule for limb lengthening through external fixation. A new methicillin-sensitive Staphylococcus aureus occurred at the same site 2.5 years later but was easily treated, and the 3-year follow-up showed no other recurrences or complications.

摘要

摩根摩根菌是一种兼性厌氧的革兰氏阴性肠杆菌。有少数几例骨骼肌肉感染的病例被记录下来。我们报告了一例 9 岁男孩的病例,他在索引外固定术治疗肢体长度差异 1 年后患有骨髓炎。我们的患者最初表现为远端内侧胫骨固定部位的伤口引流,但 X 光片未见异常。经过 1 个月的随访,初始抗生素治疗失败,培养结果显示为摩根摩根菌。他接受了切开引流和外固定器取出术,在药敏试验后改变了抗生素治疗方案。新的抗生素方案治疗 30 天后症状缓解,患者重新开始接受外固定肢体延长的治疗计划。2.5 年后同一部位出现新的耐甲氧西林金黄色葡萄球菌,但很容易治疗,3 年随访未见其他复发或并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3577/9771176/c05d461b99d3/jagrr-6-e22.00171-g001.jpg

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