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由罕见病原菌摩根摩根菌引起的骨髓炎中的生物膜:一例报告

Biofilm in Osteomyelitis caused by a Rare Pathogen, Morganella morganii : A Case Report.

作者信息

De Asmita, Raj Hirak Jyoti, Maiti Prasanta Kumar

机构信息

Post Graduate Student, Department of Microbiology, Institute of Post-Graduate Medical Education and Research , Kolkata, India .

Assistant Professor, Department of Microbiology, Institute of Post-Graduate Medical Education and Research , Kolkata, India .

出版信息

J Clin Diagn Res. 2016 Jun;10(6):DD06-8. doi: 10.7860/JCDR/2016/18666.7990. Epub 2016 Jun 1.

Abstract

Morganella morganii is a member of Enterobacteriaceae family, whose natural habitat is the human gastrointestinal tract. It rarely causes infection alone and is generally encountered in immunosuppressed patients. Osteoarticular pathologies are not commonly observed with Morganella morganii and infections by it have high mortality rate. Biofilm colonization is a causative factor behind the chronicity and/or refractoriness of certain infections. Biofilms colonize on inert medical devices, prosthesis, fibrosed tissues, sinus tracts as well as dead bones as in case of chronic osteomyelitis. Morganella morganii is not a common pathogen to produce biofilm. In this case report, we present a 56-year-old male patient with chronic osteomyelitis of right proximal tibia caused by biofilm producing strain of Morganella morganii, following trauma.

摘要

摩根氏摩根菌是肠杆菌科的一员,其自然栖息地是人类胃肠道。它很少单独引起感染,通常在免疫抑制患者中出现。摩根氏摩根菌较少引发骨关节炎病变,其感染的死亡率很高。生物膜定植是某些感染的慢性化和/或难治性的一个致病因素。生物膜会在惰性医疗设备、假体、纤维化组织、窦道以及慢性骨髓炎情况下的死骨上定植。摩根氏摩根菌不是产生生物膜的常见病原体。在本病例报告中,我们呈现了一名56岁男性患者,其右胫骨近端慢性骨髓炎由创伤后产生生物膜的摩根氏摩根菌菌株引起。

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[Osteomyelitis of the rib due to Morganella morganii].
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