Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.
Division of Pediatric Nephrology, Center for Pediatrics and Adolescent Medicine, Heidelberg University Hospital, Im Neuenheimer Feld 430, 69120, Heidelberg, Germany.
Pediatr Nephrol. 2023 Nov;38(11):3519-3528. doi: 10.1007/s00467-023-05894-1. Epub 2023 Feb 3.
Hypertension is frequent in children with chronic kidney disease (CKD). Its prevalence varies according to CKD stage and cause. It is relatively uncommon in children with congenital kidney disease, while acquired kidney disease is associated with a higher prevalence of hypertension. Studies in children with CKD utilizing ambulatory blood pressure monitoring also showed a high prevalence of masked hypertension. Uncontrolled and longstanding hypertension in children is associated with progression of CKD. Aggressive treatment of high blood pressure should be an essential part of care to delay CKD progression in children.
高血压在慢性肾脏病(CKD)患儿中很常见。其患病率因 CKD 分期和病因而异。在先天性肾脏疾病患儿中相对少见,而获得性肾脏疾病与高血压患病率较高相关。利用动态血压监测的 CKD 患儿研究也显示出隐匿性高血压的高患病率。儿童高血压得不到控制和长期存在与 CKD 进展有关。积极治疗高血压应成为儿童延缓 CKD 进展的护理的重要组成部分。