[Relationship between mononuclear infiltration of the epidermis and its hyperplasia after auto- and allotransplantation of the full-thickness skin of mice].

Histological and histochemical studies of the back skin were carried out with morphometry on the 1st, 2nd, 3rd, 6th, and 9th days after auto- or allotransplantation of its full thickness graft in 60 lineal (C3H) and random-bred mice. In both kinds of transplantation, mononuclear infiltration of the epidermis of the graft and the surrounding skin was established. A correlation between the intensity of this infiltration and the thickness of the epidermis in the skin surrounding the grafts and in the autograft was established. In allotransplantation, there was no such correlation in the graft. No mononuclear cells were found in regeneration layers of the epidermis. It is suggested that epidermis regeneration is stimulated by autogenous lymphocytes.