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[胸壁异常的发病机制——肋骨软骨的电子显微镜研究及微量元素分析]

[Pathogenesis of chest wall abnormalities--electron microscopy studies and trace element analysis of rib cartilage].

作者信息

Rupprecht H, Hümmer H P, Stöss H, Waldherr T

机构信息

Kinderchirurgische Abteilung, Chirurgischen Universitätsklinik Erlangen.

出版信息

Z Kinderchir. 1987 Aug;42(4):228-9. doi: 10.1055/s-2008-1075590.

Abstract

In 71 patients with chest deformity (Group B) and in 43 patients who underwent thoracotomy due to heart disease (Group BN), cartilage of the ribs was removed intraoperatively. Analyses of trace elements showed a highly significant decrease in zinc, coupled with a significant increase in magnesium and calcium in Group B. Electron microscope studies in the cartilage of patients with chest deformity revealed chondrocytes with a normal structure only in some parts, but many degenerative altered chondrocytes with vacuoles of fat and osmiophilic depositions, as well as atypical fibrils and so-called "long-spacing collagen".

摘要

在71例胸部畸形患者(B组)和43例因心脏病接受开胸手术的患者(BN组)中,术中切除了肋骨软骨。微量元素分析显示,B组锌含量显著降低,同时镁和钙含量显著升高。对胸部畸形患者软骨的电子显微镜研究发现,仅部分软骨细胞结构正常,但许多软骨细胞发生退行性改变,出现脂肪空泡和嗜锇沉积物,以及非典型纤维和所谓的“长间距胶原”。

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