Watanabe Sota, Mizojiri Gaku, Sada Akitada, Kai Hiroki, Takeda Koki, Masuike Yasunori, Nagasawa Yoshinobu, Maruyama Kentaro, Lee Kyowon, Oka Hiroshi, Ohata Mai, Takeshita Atsushi
Dept. of Surgery, Moriguchi Keijinkai Hospital.
Gan To Kagaku Ryoho. 2022 Dec;49(13):1768-1770.
A 68-year-old woman with a chief complaint of obstructive jaundice was referred to our hospital. She was diagnosed with gallbladder cancer with invasion to the liver, extrahepatic bile duct, right hepatic artery and portal vein. After endoscopic retrograde biliary drainage, she received chemotherapy with gemcitabine and cisplatin. After 9 courses, the size of the tumor and the lymph nodes decreased, and we planned surgery. There were no unresectable factors, and the right hepatic artery and portal vein were detached from the tumor. We performed a subtotal stomach-preserving pancreaticoduodenectomy and gallbladder bed resection. We then performed adjuvant chemotherapy with S-1 for 1 year. The patient remains alive without recurrence, 5 years after the surgery. We report the case of advanced gallbladder cancer with downstaging after GC therapy.
一名以梗阻性黄疸为主诉的68岁女性被转诊至我院。她被诊断为胆囊癌,侵犯肝脏、肝外胆管、右肝动脉和门静脉。在内镜逆行胆管引流术后,她接受了吉西他滨和顺铂化疗。9个疗程后,肿瘤和淋巴结大小减小,我们计划进行手术。没有不可切除因素,右肝动脉和门静脉与肿瘤分离。我们进行了保留胃的胰十二指肠次全切除术和胆囊床切除术。然后我们用S-1进行了1年的辅助化疗。术后5年,患者存活且无复发。我们报告了1例经GC治疗后降期的晚期胆囊癌病例。