Ototake Hideaki, Sato Hideaki, Muto Mitsuhisa, Nakagawa Kei, Masuda Kunihiro, Ueno Tatsuya, Goto Hitoshi, Satoh Akihiko, Asonuma Sho, Kimura Osamu, Hiramoto Keiichiro, Okata Hideki, Doi Kotaro, Miyazaki Shukichi, Shimosegawa Tooru
Dept. of Gastroenterology, South Miyagi Medical Center.
Gan To Kagaku Ryoho. 2022 Dec;49(13):1780-1782.
A 73-year-old man was presented with epigastric pain and indicated high CA19-9 levels, and computed tomography detected a tumor in the uncinate process of the pancreas infiltrated duodenum and superior mesenteric artery. The patient was diagnosed with borderline resectable pancreatic carcinoma and received neoadjuvant chemotherapy with gemcitabine and S-1. During neoadjuvant chemotherapy, the patient also received radiotherapy to control duodenal bleeding. After neoadjuvant chemotherapy, stable disease(SD)was proven on the Response Evaluation Criteria in Solid Tumors(RECIST), and subtotal stomach-preserving pancreaticoduodenectomy was performed. The pathological findings showed pancreatic adenosquamous carcinoma. After 7 days postoperatively, hepatic metastasis was detected, and after 78 days postoperatively, the patient died.