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鸢尾黄酮“鸢尾甲素”的药用重要性、药理活性及分析方面

Medicinal Importance, Pharmacological Activity and Analytical Aspects of Flavonoid 'Irisflorentin' from (L.) DC.

机构信息

Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, Uttar Pradesh, India.

出版信息

Curr Drug Res Rev. 2023;15(3):222-227. doi: 10.2174/2589977515666230202123308.

Abstract

Flavonoids are an important class of phytochemicals found to be present in plants and their derived products. Belamcanda chinensis (L.) DC has been used in Traditional Chinese medicine for multiple therapeutic purposes for a very long time. Belamcanda chinensis have been reported to have antipyretic, antidote, expectorant, antiphlogistic, and analgesic activity in the scientific fields. Scientific information on irisflorentin for its medicinal importance and pharmacological activity has been collected through electronic search engines, including Science Direct, Google, Google Scholar, PubMed, and Scopus, and analyzed in the present investigation in order to know the biological potential of irisflorentin. However, analytical aspects of irisflorentin are also discussed in the present work. Further detailed pharmacological activity data of irisflorentin have been collected and analyzed in the present work in order to know the therapeutic potential of irisflorentin in medicine. Scientific data analysis of different research work signified the biological importance and therapeutic benefit of Belamcanda chinensis and irisflorentin in medicine. Scientific data analysis revealed the biological effectiveness of irisflorentin against Parkinson's disease, inflammation, cancer, and brain disorders. Further scientific data analysis also signified the biological potential of irisflorentin for its α-glucosidase inhibitory potential and immunotherapeutic adjuvant in medicine. Metabolism and pharmacokinetic parameters have also been discussed in the present work. Analytical data showed the importance of various analytical methods for separation, identification and estimation of irisflorentin in different biological samples. Scientific data analysis of various research works signified the biological potential and therapeutic effectiveness of irisflorentin in medicine. However, clinical data of irisflorentin should be also investigated in order to know their pharmacokinetic parameters and safety issue in medicine.

摘要

类黄酮是一类重要的植物化学物质,存在于植物及其衍生产品中。射干(Belamcanda chinensis(L.)DC)在很长一段时间内一直被用于传统中药,具有多种治疗用途。射干具有解热、解毒、祛痰、消炎和止痛作用,在科学领域已有报道。为了了解鸢尾黄素的药用重要性和药理活性,通过电子搜索引擎,包括 Science Direct、Google、Google Scholar、PubMed 和 Scopus,收集了有关鸢尾黄素的科学信息,并在本研究中进行了分析,以了解鸢尾黄素的生物潜力。然而,本工作也讨论了鸢尾黄素的分析方面。为了了解鸢尾黄素在医学中的治疗潜力,本工作还收集和分析了鸢尾黄素的详细药理活性数据。对不同研究工作的科学数据分析表明,射干和鸢尾黄素在医学上具有重要的生物学意义和治疗益处。科学数据分析显示,鸢尾黄素对帕金森病、炎症、癌症和脑疾病具有生物疗效。进一步的科学数据分析还表明,鸢尾黄素具有α-葡萄糖苷酶抑制潜力和免疫治疗佐剂的生物学潜力,可用于医学。本工作还讨论了代谢和药代动力学参数。分析数据表明,各种分析方法对于分离、鉴定和评估不同生物样品中的鸢尾黄素非常重要。对各种研究工作的科学数据分析表明,鸢尾黄素在医学上具有生物潜力和治疗效果。然而,还应研究鸢尾黄素的临床数据,以了解其在医学中的药代动力学参数和安全性问题。

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