双黄酮“bilobetin”在药物中的生物学重要性：药用重要性、药理活性和分析方面。
Biological Importance of a Biflavonoid 'Bilobetin' in the Medicine: Medicinal Importance, Pharmacological Activities and Analytical Aspects.
机构信息
Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, 211007, Uttar Pradesh, India.
出版信息
Infect Disord Drug Targets. 2022;22(5):e210322202490. doi: 10.2174/1871526522666220321152036.
BACKGROUND
Flavonoid class phytochemicals are natural compounds present in different medicinal plants, vegetables and fruits. Ginkgo biloba contains significant amounts of bioflavonoid 'bilobetin'. Bilobetin is an active phytochemical used for the treatment of human health complications due to its medicinal properties and therapeutic benefit. The purpose of this work is to collect and reviewed scientific data on bilobetin from different literature sources; highlight their biological properties, pharmacological activities and analytical aspects.
METHODS
Health beneficial aspects of bilobetin have been investigated in the present work through scientific data analysis. PubMed, Google Scholar, Google, Scopus, etc. have been searched in the present work in order to collect scientific information on bilobetin. Medicinal importance and therapeutic benefit of bilobetin has been searched in the present work through these databases of bilobetin. Detailed pharmacological activities of bilobetin have been reviewed in the present work through literature data analysis of various scientific research works. However, analytical data of bilobetin were also collected and reviewed in the present reaserch.
RESULTS
Literature data analysis of bilobetin in the present work revealed the medicinal properties and therapeutic potential of bilobetin mainly due to its anti-fungal, anti-inflammatory, anti-oxidant, antihyperlipidemic, and anti-proliferative activities. Literature data analysis revealed the effectiveness of bilobetin on osteoporosis, glucose metabolism, adipocytes, SARS CoV-2, Influenza A virus and human thrombin. Scientific data also revealed the importance of different analytical techniques for the isolation, separation, identification, and quantification of bilobetin.
CONCLUSION
Scientific data analysis revealed biological importance and pharmacological activities of bilobetin in the health sector.
背景
类黄酮植物化学物质是存在于不同药用植物、蔬菜和水果中的天然化合物。银杏叶含有大量的生物类黄酮“银杏素”。银杏素是一种具有药用特性和治疗益处的活性植物化学物质，用于治疗人类健康并发症。本工作的目的是从不同文献来源收集和综述银杏素的科学数据；强调其生物学特性、药理学活性和分析方面。
方法
本工作通过科学数据分析研究银杏素的健康有益方面。本工作通过 PubMed、Google Scholar、Google、Scopus 等搜索引擎检索了有关银杏素的科学信息。本工作通过这些银杏素数据库检索了银杏素的药用重要性和治疗益处。本工作通过对各种科学研究工作的文献数据分析综述了银杏素的详细药理学活性。然而，本研究还收集和综述了银杏素的分析数据。
结果
本工作对银杏素的文献数据分析揭示了银杏素的药用特性和治疗潜力，主要归因于其抗真菌、抗炎、抗氧化、抗高脂血症和抗增殖活性。文献数据分析显示银杏素对骨质疏松症、葡萄糖代谢、脂肪细胞、SARS CoV-2、甲型流感病毒和人凝血酶的有效性。科学数据还揭示了不同分析技术在银杏素的分离、分离、鉴定和定量中的重要性。
结论
科学数据分析揭示了银杏素在健康领域的生物学重要性和药理学活性。
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