Department of Large Animal Medicine, University of Georgia, Athens, Georgia, USA.
Department of Population Health, University of Georgia, Athens, Georgia, USA.
Equine Vet J. 2023 Nov;55(6):944-961. doi: 10.1111/evj.13930. Epub 2023 Feb 16.
Equine practitioners require recommendations that support antimicrobial stewardship and avoid generating resistance to medically important antibiotics. This review examines current inadequacies in antimicrobial stewardship standards within the veterinary community, related to antimicrobial categorisation and prescribing practices. Resistance to cephalosporin antibiotics in horses is also described. Properties of cephalosporin antibiotics are outlined and equine-specific studies of ceftiofur, a third-generation cephalosporin antibiotic with medical importance, are detailed. Readers are provided with recommendations that encourage appropriate use of ceftiofur, citing the evidence available in horses.
马科医生需要有支持抗生素管理和避免产生针对重要医学抗生素的耐药性的建议。本综述检查了目前兽医界中在抗生素管理标准方面的不足，涉及抗生素分类和处方实践。还描述了马科动物中头孢菌素类抗生素的耐药性。概述了头孢菌素类抗生素的特性，并详细介绍了具有医学重要性的第三代头孢菌素抗生素头孢噻呋在马科动物中的具体研究。为读者提供了鼓励在马科动物中合理使用头孢噻呋的建议，并引用了现有的相关证据。
