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[已撤回] 二甲双胍通过抑制乳腺癌中的 Sonic 刺猬信号通路发挥抗癌作用。

[Retracted] Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer.

作者信息

Fan Cong, Wang Yunshan, Liu Ziming, Sun Ying, Wang Xiuwen, Wei Guangwei, Wei Junmin

机构信息

Department of Chemotherapy, Cancer Center, Qilu Hospital, Shandong University, Jinan, Shandong 250012, P.R. China.

Department of Human Anatomy and Key Laboratory of Experimental Teratology, Ministry of Education, Shandong University School of Medicine, Jinan, Shandong 250012, P.R. China.

出版信息

Int J Mol Med. 2023 Mar;51(3). doi: 10.3892/ijmm.2023.5227. Epub 2023 Feb 3.

Abstract

Following the publication of this paper, it was drawn to the Editor's attention by concerned readers that several of the cellular images shown in Figs. 6A and 8A, the scratch‑wound assay images shown in Fig. 5A, the western blotting data in Figs. 2C and 7A and the Matrigel invasion assays in Fig. 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to , the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused. [International Journal of Molecular Medicine 36: 204‑214, 2015; DOI: 10.3892/ijmm.2015.2217].

摘要

在本文发表后,相关读者引起了编辑的注意,图6A和8A中所示的一些细胞图像、图5A中所示的划痕试验图像、图2C和7A中的蛋白质印迹数据以及图5C中的基质胶侵袭试验与不同作者在其他文章中以不同形式出现的数据惊人地相似。由于上述文章中有争议的数据在提交给本期刊之前已在其他地方发表,或已在考虑发表,编辑决定将本文从该期刊撤回。已要求作者对这些问题作出解释,但编辑部未收到答复。编辑就由此造成的任何不便向读者表示歉意。[《国际分子医学杂志》36: 204 - 214, 2015;DOI: 10.3892/ijmm.2015.2217]

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