Quinnipiac University, North Haven, CT, USA.
Connecticut Orthopaedics, Hamden, CT, USA.
Hand (N Y). 2023 May;18(3):NP16-NP18. doi: 10.1177/15589447231151260. Epub 2023 Feb 3.
Paraneoplastic syndromes represent the body's immune response to an underlying malignancy. The autoimmune response to cancer can manifest itself in multiple ways, including swelling, thickening, and changes in the hand. We report the case of a 65-year-old man who presented with hand swelling that was initially attributed to a work-related finger laceration. The patient developed edema and stiffness in the hand, which was subsequently diagnosed as Waldenström macroglobulinemia. Hand surgeons should be aware that atypical hand and wrist symptoms should raise the suspicion for the potential of a paraneoplastic syndrome and an underlying malignancy.
副肿瘤综合征代表了机体对潜在恶性肿瘤的免疫反应。癌症的自身免疫反应可以以多种方式表现出来，包括手部肿胀、增厚和变化。我们报告了一例 65 岁男性患者，其手部肿胀最初归因于与工作相关的手指裂伤。患者手部出现水肿和僵硬，随后被诊断为瓦尔登斯特伦巨球蛋白血症。手部外科医生应该意识到，不典型的手部和腕部症状应该引起对潜在副肿瘤综合征和恶性肿瘤的怀疑。
